- ADMINISTRATIVE CORE The Administrative Core of the Mayo Alzheimer's Disease Research Center (ADRC) will coordinate the overall research activities of the Center at both sites in Rochester, Minnesota, and Jacksonville, Florida. The Core will oversee the integration of the research activities of the Center in pursuing the Specific Aims. The Core will interact with program officials at the National Institute on Aging and will be responsible for personnel and financial matters. The Core will also coordinate data transfer and communications with the National Alzheimer's Coordinating Center. The Mayo ADRC has an active Pilot Project Program, and the Core will solicit applications, review them and communicate with the National Institute on Aging on selected pilot projects. The Core will also convene the External Advisory Committee for the Mayo ADRC and hold annual meetings. The Internal Steering Committee of the ADRC will be coordinated by the Administrative Core, and monthly videoconferences will be held between Rochester and Jacksonville. The Core will also oversee the activities of the three research projects and support their research missions. Ultimately, the Administrative Core will be responsible for maintaining research along the themes of the ADRC: 1) to evaluate subjects along the AD spectrum and 2) to support research projects for AD-related dementias.

Public Health Relevance

- ADMINISTRATIVE CORE Alzheimer's disease is a complex condition affecting tens of millions of people worldwide. The Mayo Alzheimer's Disease Research Center is focusing much of its effort on understanding the basis for the disease, improving diagnoses, monitoring biomarkers and exploring new potential treatments. The Administrative Core is an essential element in the Center and is responsible for coordinating the activities of the cores and projects as well as communicating with the National Institute on Aging and other Alzheimer's centers. The Core is ultimately responsible for all the research conducted in the Center.

National Institute of Health (NIH)
Specialized Center (P50)
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Special Emphasis Panel (ZAG1)
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Mayo Clinic, Rochester
United States
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Kertesz, A; Finger, E; Murrell, J et al. (2015) Progressive supranuclear palsy in a family with TDP-43 pathology. Neurocase 21:178-84
Zhang, Bing; Ferman, Tanis J; Boeve, Bradley F et al. (2015) MRS in mild cognitive impairment: early differentiation of dementia with Lewy bodies and Alzheimer's disease. J Neuroimaging 25:269-74
Nedelska, Zuzana; Ferman, Tanis J; Boeve, Bradley F et al. (2015) Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies. Neurobiol Aging 36:452-61
Steffen, Teresa M; Boeve, Bradley F; Petersen, Cheryl M et al. (2014) Long-term exercise training for an individual with mixed corticobasal degeneration and progressive supranuclear palsy features: 10-year case report follow-up. Phys Ther 94:289-96
Shinohara, Mitsuru; Fujioka, Shinsuke; Murray, Melissa E et al. (2014) Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease. Brain 137:1533-49
van Blitterswijk, Marka; Mullen, Bianca; Wojtas, Aleksandra et al. (2014) Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Mol Neurodegener 9:38
Cannon, Ashley; Bieniek, Kevin F; Lin, Wen-Lang et al. (2014) Concurrent variably protease-sensitive prionopathy and amyotrophic lateral sclerosis. Acta Neuropathol 128:313-5
Mielke, Michelle M; Weigand, Stephen D; Wiste, Heather J et al. (2014) Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimers Dement 10:779-89
Graff-Radford, Jonathan; Murray, Melissa E; Lowe, Val J et al. (2014) Dementia with Lewy bodies: basis of cingulate island sign. Neurology 83:801-9
Winslow, Ashley R; Moussaud, Simon; Zhu, Liya et al. (2014) Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease. Brain 137:1958-70

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