The primary goals of the Information Transfer Core are to educate both the lay and professional communities and to disseminate information, not only on Alzheimer's Disease (AD), but also information arising from research at the ADRC.
In Specific Aim 1, Dr. Harrell will join with two pharmaceutical companies (Pfizer and Eisai) to bring education on AD to physicians. It will be the responsibility of the pharmaceutical companies to arrange and manage the locations (i.e. grand rounds, dinner lectures, etc.) and invite the targeted physician population (internal medicine, family practitioners, general practitioners). Dr. Harrell will have complete control over lecture content, as she will not be paid an honorarium or travel expenses by the pharmaceutical companies. Lectures will be distributed throughout Alabama (5 districts, 3/5 rural), so that each district will receive 4 lectures in 5 years. A pre- and post-AD knowledge test (developed at UAB-ADC) will be given. After scoring, these will be returned to physicians along with information that may help them.
Specific Aim 2 will provide opportunities to the community (in particular the African-American community) to learn about AD and thereby the importance of 1) obtaining an appropriate evaluation for dementia and 2) participating in research studies. A variety of modalities will e used to reach the lay and paraprofessional communities, including a free Speakers Bureau, caregiver newsletters and MedWise newsletter which reaches 120,000 individuals over 50, giving lectures at nutrition sites, churches and health fairs. A 1-800 telephone line will be installed so that individuals may request information on AD. Packets containing materials on AD will be distributed. We will continue our annual ADC CME conference.
In Specific Aim 3, we will develop a home page on the World Wide Web on the Internet for our ADRC.
In Specific Aim 4, we will disseminate information about research, both clinical and basic science, performed at our ADRC. Many media modalities will be employed to accomplish this goal. Overall, however, it should enhance the visibility of our ADRC and bring important information to both the lay and professional communities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG016582-04
Application #
6593388
Study Section
Project Start
2002-06-01
Project End
2003-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
4
Fiscal Year
2002
Total Cost
$157,506
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Lassen-Greene, Caroline L; Steward, Kayla; Okonkwo, Ozioma et al. (2017) Mild Cognitive Impairment and Changes in Everyday Function Over Time: The Importance of Evaluating Both Speed and Accuracy. J Geriatr Psychiatry Neurol 30:220-227
Sims, Rebecca (see original citation for additional authors) (2017) Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet 49:1373-1384
Niccolai, Lindsay M; Triebel, Kristen L; Gerstenecker, Adam et al. (2017) Neurocognitive Predictors of Declining Financial Capacity in Persons with Mild Cognitive Impairment. Clin Gerontol 40:14-23
Jun, Gyungah R; Chung, Jaeyoon; Mez, Jesse et al. (2017) Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement 13:727-738
Karch, Celeste M; Ezerskiy, Lubov A; Bertelsen, Sarah et al. (2016) Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One 11:e0148717
Mez, Jesse; Mukherjee, Shubhabrata; Thornton, Timothy et al. (2016) The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable. Neurobiol Aging 41:115-121
Ridge, Perry G; Hoyt, Kaitlyn B; Boehme, Kevin et al. (2016) Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging 41:200.e13-200.e20
Hohman, Timothy J; Bush, William S; Jiang, Lan et al. (2016) Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiol Aging 38:141-150
Jun, G; Ibrahim-Verbaas, C A; Vronskaya, M et al. (2016) A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry 21:108-17
Hohman, Timothy J; Cooke-Bailey, Jessica N; Reitz, Christiane et al. (2016) Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement 12:233-43

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