CORE E: ABSTRACT This is a proposal to renew the Outreach, Recruitment, and Education Core (Ed Core) for the UCSF Alzheimer's Disease Research Center (ADRC). The core supports the UCSF ADRC by ensuring a steady flow of participants with FTD-spectrum disorders, CJD, amnestic and non-amnestic AD, controls and Chinese- Americans into the Clinical Core, while providing an unparalleled educational environment for emerging researchers and early clinical trainees. The core will focus on four aims, which will continue the current efforts and extend them in the following ways. (1) For Education of Community Professionals, we will maintain outreach to Bay Area professionals with lecturing, organization of conferences, and continued contact with colleagues at the Kaiser Permanente Medical Center (KPMC) in San Francisco. In addition, we will strengthen these efforts by expanding our outreach to KPMC, establishing a new relationship with the HOPE program in Marin County, and organizing a new series of recurring lectures in partnership with the Northern California Alzheimer's Association and other major Bay Area medical centers. (2) For Community Education, we will continue community lectures and maintain and update our web-based resources including our website, Facebook page, Twitter feed, and Blog. In addition, we will improve our website by creating a section on young-onset/non-amnestic subtypes of Alzheimer's disease. (3) For Outreach to Chinese Americans, we will continue our clinical consultation program in Chinatown and partnerships with community organizations to educate laypersons and health providers serving the Chinese American community about neurodegenerative disease. In addition, we will further facilitate the ability of Chinese Americans to participate in research by translating the new UDS neuropsychological battery into Chinese and making these materials available to all centers via NACC, and developing the EXAMINER-C as a frontal assessment battery for Chinese individuals by creating preliminary normative data. (4) For Research and Clinical Training at UCSF, we will maintain our fellowship training programs with a rich set of clinical and experimental resources and continue to welcome medical early clinical trainees to our month long behavioral neurology rotation. In addition, we will enrich and expand these experiences by establishing a new statistical seminar for our clinical research fellows and opening the neurobehavioral rotation to students and postdoctoral fellows in the UCSF Neuroscience program.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4 (J1))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Francisco
San Francisco
United States
Zip Code
Mansoor, Yael; Jastrzab, Laura; Dutt, Shubir et al. (2015) Memory profiles in pathology or biomarker confirmed Alzheimer disease and frontotemporal dementia. Alzheimer Dis Assoc Disord 29:135-40
Wagshal, Dana; Sankaranarayanan, Sethu; Guss, Valerie et al. (2015) Divergent CSF ? alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 86:244-50
Greene, Meredith; Steinman, Michael A; McNicholl, Ian R et al. (2014) Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection. J Am Geriatr Soc 62:447-53
Rosen, Howard J; Alcantar, Oscar; Zakrzewski, Jessica et al. (2014) Metacognition in the behavioral variant of frontotemporal dementia and Alzheimer's disease. Neuropsychology 28:436-47
Beecham, Gary W; Hamilton, Kara; Naj, Adam C et al. (2014) Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet 10:e1004606
Minikel, Eric Vallabh; Zerr, Inga; Collins, Steven J et al. (2014) Ascertainment bias causes false signal of anticipation in genetic prion disease. Am J Hum Genet 95:371-82
Laforce Jr, Robert; Tosun, Duygu; Ghosh, Pia et al. (2014) Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology. Neuroimage Clin 4:508-16
El Magraoui, Fouzi; Eisenacher, Martin; Schrötter, Andreas et al. (2014) Developing new methods to answer old and new questions in neurodegenerative diseases: 21(st) Workshop of the HUPO Brain Proteome Project (HBPP) 23-24 January 2014, Honolulu, Hawaii. Proteomics 14:1308-10
James, Bryan D; Leurgans, Sue E; Hebert, Liesi E et al. (2014) Contribution of Alzheimer disease to mortality in the United States. Neurology 82:1045-50
Walsh, Christine M; Wilkins, Sarah; Bettcher, Brianne Magouirk et al. (2014) Memory consolidation in aging and MCI after 1 week. Neuropsychology 28:273-80

Showing the most recent 10 out of 177 publications