Abstract

The Clinical, Cognitive, and Analytical Core will provide management of human studies, maintenance of a shared database, and statistical oversight for Projects I, II, and III. These activities include recmiting, screening, consent and enrollment of study participants;coordinating scheduling laboratory tests, neurocognitive tests, transcranial Doppler ultrasonography and brain imaging;and database management and statistical analysis. Establishing these functions in a Core assures continuity of recruitment and procedures, cost savings, quality sample collection, and data processing.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
1P50AG044170-01
Application #
8367412
Study Section
Special Emphasis Panel (ZRG1-EMNR-Q (50))
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
1
Fiscal Year
2012
Total Cost
$288,817
Indirect Cost
$107,171

  Institution

Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905

  Publications

Ramanan, Vijay K; Przybelski, Scott A; Graff-Radford, Jonathan et al. (2018) Statins and Brain Health: Alzheimer's Disease and Cerebrovascular Disease Biomarkers in Older Adults. J Alzheimers Dis 65:1345-1352
Rocca, Walter A; Gazzuola Rocca, Liliana; Smith, Carin Y et al. (2018) Personal, reproductive, and familial characteristics associated with bilateral oophorectomy in premenopausal women: A population-based case-control study. Maturitas 117:64-77
Mielke, Michelle M; Hagen, Clinton E; Xu, Jing et al. (2018) Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography. Alzheimers Dement 14:989-997
Barnes, Jill N; Harvey, Ronée E; Miller, Kathleen B et al. (2018) Cerebrovascular Reactivity and Vascular Activation in Postmenopausal Women With Histories of Preeclampsia. Hypertension 71:110-117
Gao, Catherine C; Kapoor, Ekta; Lipford, Melissa C et al. (2018) Association of vasomotor symptoms and sleep apnea risk in midlife women. Menopause 25:391-398
Laughlin-Tommaso, Shannon K; Khan, Zaraq; Weaver, Amy L et al. (2018) Cardiovascular and metabolic morbidity after hysterectomy with ovarian conservation: a cohort study. Menopause 25:483-492
Wennberg, Alexandra M V; Hagen, Clinton E; Edwards, Kelly et al. (2018) Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging. Int J Geriatr Psychiatry 33:1114-1120
Knopman, David S; Lundt, Emily S; Therneau, Terry M et al. (2018) Joint associations of ?-amyloidosis and cortical thickness with cognition. Neurobiol Aging 65:121-131
Wenning, Gregor; Trojanowski, John Q; Kaufmann, Horacio et al. (2018) Is multiple system atrophy an infectious disease? Ann Neurol 83:10-12
Kattah, Andrea G; Smith, Carin Y; Gazzuola Rocca, Liliana et al. (2018) CKD in Patients with Bilateral Oophorectomy. Clin J Am Soc Nephrol 13:1649-1658

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