The major goal of the Psoriasis CORT at Case is to integrate basic, clinical and translational resources inorder to promote the progress and quality of research in psoriasis. In order to accomplish this, the CORT willadd two cores to the array of fully functional existing cores within the Skin Diseases Research Center. TheBiostatistics Core will provide appropriate methodological support for skin-related research through arecognized and accessible central unit. By integrating three complementary functions -service, researchand education - the efficiency and quality of research endeavors of CORT investigators will be boosted. Theservices covered will range from the assistance in planning and analysis of protocols and writing ofmanuscripts, to the provision of computational resources. Also, a wide range of specialized analyses will beprovided, including study design, survival, longitudinal, multivariate, diagnostic testing, statistical imageanalysis, meta-analysis, and consultation on microarray data. The latter will constitute the bridge betweenthe operations of the Biostatistics and the Systems Biology Cores, extensively used by the four projects ofthe CORT. Finally, an education mission focused on principles of experimental and clinical research designwill allow investigators to conceptualize their studies in a more efficient way.
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