This Core brings together biostatisticians and bioinformaticians who are experienced in the scientific areas covered by the SPORE and who are already close collaborators with SPORE lead investigators.
Core researchers have a track record of methodological contributions, considerable experience in the design and analysis of both laboratory and clinical data, and expertise in biomarker discovery, evaluation, validation and disease prediction modeling to facilitate translation of the biomarker-based projects. Core members will provide integrated support for the design and analysis of SPORE major projects and pilot projects.
|Lugade, Amit A; Bogner, Paul N; Thatcher, Thomas H et al. (2014) Cigarette smoke exposure exacerbates lung inflammation and compromises immunity to bacterial infection. J Immunol 192:5226-35|
|Pu, Jiantao; Wang, Zhimin; Gu, Suicheng et al. (2014) Pulmonary fissure integrity and collateral ventilation in COPD patients. PLoS One 9:e96631|
|Zhou, Yu Jerry; Messmer, Michelle Nicole; Binder, Robert Julian (2014) Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91. Cancer Immunol Res 2:217-28|
|Gu, Suicheng; Meng, Xin; Sciurba, Frank C et al. (2014) Bidirectional elastic image registration using B-spline affine transformation. Comput Med Imaging Graph 38:306-14|
|Bruse, Shannon; Petersen, Hans; Weissfeld, Joel et al. (2014) Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respir Res 15:2|
|Siegfried, Jill M; Stabile, Laura P (2014) Estrongenic steroid hormones in lung cancer. Semin Oncol 41:5-16|
|Landreneau, Rodney J; Normolle, Daniel P; Christie, Neil A et al. (2014) Recurrence and survival outcomes after anatomic segmentectomy versus lobectomy for clinical stage I non-small-cell lung cancer: a propensity-matched analysis. J Clin Oncol 32:2449-55|
|Stabile, Laura P; Rothstein, Mary E; Gubish, Christopher T et al. (2014) Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF. J Thorac Oncol 9:1285-93|
|Siegfried, Jill M (2014) Smoking out reproductive hormone actions in lung cancer. Mol Cancer Res 12:24-31|
|Burns, Timothy F; Stabile, Laura P (2014) Targeting the estrogen pathway for the treatment and prevention of lung cancer. Lung Cancer Manag 3:43-52|
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