The purpose of the Administration Core is to support the translational research objectives of the UCLA SPORE in Prostate Cancer by serving as the organizational hub. The Core is responsible for the oversight of our SPORE by providing scientific leadership and administration for the proposed translational research projects, shared core resources. Developmental Research (DRP) and Career Development Programs (CDP). The overall Specific Aims are: 1) Organizational leadership for successful SPORE conduct;2) Oversight and administrative support for daily SPORE activities;3) Scientific management of the SPORE, including scientific review of projects and cores to ensure scientific goals are met;4) Administration of the DRP and CDP;5) Responsibility for maintaining fiscal and budgetary functions;6) Organization and conduct of regular SPORE meetings and seminars. Including the Annual UCLA SPORE in Prostate Cancer Symposium, quarterly investigator meetings, attendance at the NCI Translational Science meeting and relevant NIH/NCI workshops;7) Compliance with all UCLA, NCI, and Federal regulations and requirements including appropriate animal subject approval maintenance, appropriate human subject approval maintenance, and minority inclusion policy monitoring;8) A Data/Resource Sharing Plan implemented by project and core investigators;9) Liaison service for SPORE investigators, collaborators, and committee members, including the External Advisory Board (EAB), Internal Advisory Board (IAB), Executive Committee and Patient Advocacy Group, and responsibility for communication and consultation with the NCI-TRP program officer and staff;10) Implement and monitor recommendations of the External Advisory Committee, Internal Advisory Board, Executive Committee, CDP and DRP committees within the SPORE. The Administration Core is led by Robert Reiter, MD, the SPORE principal investigator, who oversees all SPORE activities. The Core's co-director is Owen Witte, MD. The Administration Core also includes expert personnel in general university operations, grants administration, financial management, computer network support and general administrative duties.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center (P50)
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Special Emphasis Panel (ZCA1-RPRB-M)
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University of California Los Angeles
Los Angeles
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Mitra, Mithun; Lee, Ha Neul; Coller, Hilary A (2018) Determining Genome-wide Transcript Decay Rates in Proliferating and Quiescent Human Fibroblasts. J Vis Exp :
Zou, Yongkang; Qi, Zhi; Guo, Weilong et al. (2018) Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3K?/?/? Inhibitor BAY1082439. Mol Cancer Ther 17:2091-2099
Henning, Susanne M; Galet, Colette; Gollapudi, Kiran et al. (2018) Phase II prospective randomized trial of weight loss prior to radical prostatectomy. Prostate Cancer Prostatic Dis 21:212-220
Miller, Eric T; Salmasi, Amirali; Reiter, Robert E (2018) Anatomic and Molecular Imaging in Prostate Cancer. Cold Spring Harb Perspect Med 8:
Navarro, H├ęctor I; Goldstein, Andrew S (2018) HoxB13 mediates AR-V7 activity in prostate cancer. Proc Natl Acad Sci U S A 115:6528-6529
Mitra, Mithun; Ho, Linda D; Coller, Hilary A (2018) An In Vitro Model of Cellular Quiescence in Primary Human Dermal Fibroblasts. Methods Mol Biol 1686:27-47
Li, Jiayun; Speier, William; Ho, King Chung et al. (2018) An EM-based semi-supervised deep learning approach for semantic segmentation of histopathological images from radical prostatectomies. Comput Med Imaging Graph 69:125-133
Kang, Jung J; Reiter, Robert E; Kummer, Nicolas et al. (2018) Wrong to be Right: Margin Laterality is an Independent Predictor of Biochemical Failure After Radical Prostatectomy. Am J Clin Oncol 41:1-5
Lee, Ha Neul; Mitra, Mithun; Bosompra, Oye et al. (2018) RECK isoforms have opposing effects on cell migration. Mol Biol Cell 29:1825-1838
Aggarwal, Rahul; Huang, Jiaoti; Alumkal, Joshi J et al. (2018) Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study. J Clin Oncol 36:2492-2503

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