; To ensure the success of the Uterine SPORE program at M. D. Anderson, the overall goal of the Administrative Core is to provide effective management and administration of all activities relating to each project, core, and developmental program in the SPORE. The Administrative Core will actively work to communicate and disseminate information within our internal SPORE investigators as well as facilitate information sharing and collaborations with other SPOREs and external constituencies. The Core will provide a structure to assure integration of diverse scientific disciplines into a unified multidisciplinary approach for achieving excellence in translational endometrial cancer research. Importantly, the Administrative Core will monitor timelines and ensure both basic science and clinical trial aims are met for all SPORE projects. The Core will provide administrative support to the individual SPORE projects, cores, and developmental programs, as well as to the Internal and External Advisory Committees and the Patient Advocates. The Core will assist in preparation of all reports, abstracts, and manuscripts resulting from SPORE activities. The Administrative Core will assure compliance with regulations at all levels and maintain communication among investigators, as well as with other translational researchers, gynecologic cancer SPOREs, the Gynecologic Oncology Group and SPOREs from other disease sites. The Core will convene all meetings, including the Executive Committee, Internal Advisory Committee, External Advisory Committee, and other educational and regulatory activities. The Administrative Core will provide support for data management and for the integration of a centralized data repository accessible by all SPORE investigators. Dr. Karen Lu, Director ofthe Administrative Core and Principal Investigator for the overall SPORE, will direct these activities with the assistance of the Co-Directors of the Administrative Core and Co-Principal Investigators forthe overall SPORE, Drs. Russell Broaddus, Thomas Burke, and George Stancel, as well as the SPORE Program Manager, Jennifer Stanley.

Public Health Relevance

The primary objective of the Uterine SPORE Administrative Core is to provide effective leadership and administrative support for a broad range of SPORE-related activities to ensure optimal progress and performance of all leaders, investigators, projects, cores, and developmental research and career development programs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA098258-10
Application #
8724917
Study Section
Special Emphasis Panel (ZCA1-RPRB-M)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
10
Fiscal Year
2014
Total Cost
$117,389
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Chen, Xiuhui; Mangala, Lingegowda S; Rodriguez-Aguayo, Cristian et al. (2018) RNA interference-based therapy and its delivery systems. Cancer Metastasis Rev 37:107-124
Ng, Patrick Kwok-Shing; Li, Jun; Jeong, Kang Jin et al. (2018) Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell 33:450-462.e10
Wang, Jue; Zhao, Wei; Guo, Huifang et al. (2018) AKT isoform-specific expression and activation across cancer lineages. BMC Cancer 18:742
Berger, Ashton C; Korkut, Anil; Kanchi, Rupa S et al. (2018) A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell 33:690-705.e9
Huang, Yan; Hu, Wei; Huang, Jie et al. (2018) Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer. Mol Cancer Ther 17:464-473
Pal, Navdeep; Broaddus, Russell R; Urbauer, Diana L et al. (2018) Treatment of Low-Risk Endometrial Cancer and Complex Atypical Hyperplasia With the Levonorgestrel-Releasing Intrauterine Device. Obstet Gynecol 131:109-116
Armbruster, Shannon D; Sun, Charlotte C; Westin, Shannon N et al. (2018) Prospective assessment of patient-reported outcomes in gynecologic cancer patients before and after pelvic exenteration. Gynecol Oncol 149:484-490
Kim, Moon Jong; Xia, Bo; Suh, Han Na et al. (2018) PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis. Dev Cell 44:582-596.e4
Bolivar, Ana M; Luthra, Rajyalakshmi; Mehrotra, Meenakshi et al. (2018) Targeted next-generation sequencing of endometrial cancer and matched circulating tumor DNA: identification of plasma-based, tumor-associated mutations in early stage patients. Mod Pathol :
Yuan, Xiaoyi; Lee, Jae W; Bowser, Jessica L et al. (2018) Targeting Hypoxia Signaling for Perioperative Organ Injury. Anesth Analg 126:308-321

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