The ICMIC(gStanford has matured from a P20 initially funded in 2000, with subsequent funding of the ICMIC PSO in 2004, to a multidisciplinary program with the expertise and infrastructure to support the growing field of multimodality molecular imaging. Dr Gambhir, the ICMIC PI, has made a conscious effort to merge his interests in radiology and molecular pharmacology to focus on the rapidly emerging field of molecular imaging. Eariier on, Dr. Gambhir was a key contributor to the UCLA-ICMIC where his lab very competently provided the ideal link between basic cancer biologists and biomedical imaging scientists. Dr. Gambhir then moved to Stanford with his lab of 20 students/postdocs in July 2003. ICMIC Co-PI, Dr. Contag, has spent a significant portion of his career focused on small animal bioluminescence optical imaging and has helped to make this technology widely available on the Stanford Campus and beyond. Together Drs. Gambhir and Contag provide an enormous breadth spanning from basic science, to pre-clinical imaging, to clinical applications of molecular imaging. Additionally, they both also have a primary emphasis on the study of cancer, and are both committed to clinical translation of molecular imaging.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA114747-10
Application #
8726917
Study Section
Special Emphasis Panel (ZCA1-SRLB-9)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
10
Fiscal Year
2014
Total Cost
$66,933
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
Chang, Edwin; Liu, Hongguang; Unterschemmann, Kerstin et al. (2015) 18F-FAZA PET imaging response tracks the reoxygenation of tumors in mice upon treatment with the mitochondrial complex I inhibitor BAY 87-2243. Clin Cancer Res 21:335-46
Ye, Deju; Shuhendler, Adam J; Pandit, Prachi et al. (2014) Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci 4:3845-3852
Casey, Stephanie C; Li, Yulin; Felsher, Dean W (2014) An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation. Immunol Res 58:282-91
Pu, Kanyi; Shuhendler, Adam J; Valta, Maija P et al. (2014) Phosphorylcholine-coated semiconducting polymer nanoparticles as rapid and efficient labeling agents for in vivo cell tracking. Adv Healthc Mater 3:1292-8
Bu, Lihong; Shen, Baozhong; Cheng, Zhen (2014) Fluorescent imaging of cancerous tissues for targeted surgery. Adv Drug Deliv Rev 76:21-38
Lazari, Mark; Collins, Jeffrey; Shen, Bin et al. (2014) Fully automated production of diverse 18F-labeled PET tracers on the ELIXYS multireactor radiosynthesizer without hardware modification. J Nucl Med Technol 42:203-10
Cheng, Kai; Kothapalli, Sri-Rajasekhar; Liu, Hongguang et al. (2014) Construction and validation of nano gold tripods for molecular imaging of living subjects. J Am Chem Soc 136:3560-71
Do, John; Foster, Deshka; Renier, Corinne et al. (2014) Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models. Breast Cancer Res Treat 144:93-101
Fan, Quli; Cheng, Kai; Hu, Xiang et al. (2014) Transferring biomarker into molecular probe: melanin nanoparticle as a naturally active platform for multimodality imaging. J Am Chem Soc 136:15185-94
Levi, Jelena; Sathirachinda, Ataya; Gambhir, Sanjiv S (2014) A high-affinity, high-stability photoacoustic agent for imaging gastrin-releasing peptide receptor in prostate cancer. Clin Cancer Res 20:3721-9

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