The University of Michigan Cancer Center Gl SPORE Administrative Core is reponsible for leadership, guidance, and management. The Administrative Core oversees all aspects and performs numerous duties across the expansive scope of the SPORE. These duties are to: 1. Provide scientific leadership, oversee scientific progress, ensures integration and asserts translational focus of all components of the Gl SPORE. 2. Provide logistical and coordinating support for all Gl SPORE operations;3. Manage and oversee the budgets of ail SPORE components;4. Administer developmental research projects and career development awards;5. Facilitate interactions between the Gl SPORE, other SPOREs, and the NCI;6. Communicate with NCI program staff and coordinate submission of required reports;7. Ensure recruitment of underserved minorities to all Gl SPORE projects and research support opportunities;8. Assure compliance with regulations regarding animals in research;9. Coordinate with the Biostatistics and Bioinformatics Core, the Cancer Center's Clinical Trials Office, and support Gl SPORE translational research in humans, and to ensure compliance Good Clinical Practice. Dean E. Brenner, M.D. will serve as prinicipal investigator of the Administrative Core. Dr. Brenner will oversee the day to day operations including all SPORE funcitons, budget, scientific and administrative decisions. He will serve as Chair of the SPORE Operations Committee and signs off on all Operations Committee decisions. Diane Simeone, M.D. will serve as co-principal investigator of the Administrative Core. A co-program director of the Cancer Center Gl Program, she serves as a critical link to the Gl Program. She will oversee the Career Development and Developmental Research Programs and she will oversee the use of SPORE discretionary funds. She will organize the joint SPORE and Gl Program retreats. Ms. Mary Rexer-Bluhm will serve as interim SPORE administrator until a permanent administrator is appointed. Ms. Rexer-Bluhm has provided administrative support for 10 SPORE submissions over the last 13 years for the University of Michigan Cancer Center and serves as the administrative supervisor for the SPORE Program Managers. This Core provides the frameworic to support the success and the mission of the UMCCC SPORE as a cohesive group of investigators committed to the development of translational research in Gl cancers.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA130810-03
Application #
8380364
Study Section
Special Emphasis Panel (ZCA1-GRB-I)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
3
Fiscal Year
2012
Total Cost
$246,476
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Triner, Daniel; Xue, Xiang; Schwartz, Andrew J et al. (2017) Epithelial Hypoxia-Inducible Factor 2? Facilitates the Progression of Colon Tumors through Recruiting Neutrophils. Mol Cell Biol 37:
An, Mingrui; Lohse, Ines; Tan, Zhijing et al. (2017) Quantitative Proteomic Analysis of Serum Exosomes from Patients with Locally Advanced Pancreatic Cancer Undergoing Chemoradiotherapy. J Proteome Res 16:1763-1772
Djuric, Zora; Aslam, Muhammad Nadeem; Simon, Becky R et al. (2017) Effects of fish oil supplementation on prostaglandins in normal and tumor colon tissue: modulation by the lipogenic phenotype of colon tumors. J Nutr Biochem 46:90-99
Dosch, Joseph; Ziemke, Elizabeth; Wan, Shanshan et al. (2017) Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency. Oncotarget 8:65090-65099
Ulintz, Peter J; Greenson, Joel K; Wu, Rong et al. (2017) Lymph Node Metastases in Colon Cancer are Polyclonal. Clin Cancer Res :
Stoffel, Elena M; Koeppe, Erika; Everett, Jessica et al. (2017) Germline Genetic Features of Young Individuals with Colorectal Cancer. Gastroenterology :
Djuric, Zora (2017) Obesity-associated cancer risk: the role of intestinal microbiota in the etiology of the host proinflammatory state. Transl Res 179:155-167
Parsels, Leslie A; Karnak, David; Parsels, Joshua D et al. (2017) PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors. Mol Cancer Res :
Demitrack, Elise S; Samuelson, Linda C (2017) Notch as a Driver of Gastric Epithelial Cell Proliferation. Cell Mol Gastroenterol Hepatol 3:323-330
Djuric, Zora; Aslam, Muhammad Nadeem; Simon, Becky R et al. (2017) Fatty acid and lipidomic data in normal and tumor colon tissues of rats fed diets with and without fish oil. Data Brief 13:661-666

Showing the most recent 10 out of 95 publications