The principal role of the Administrative Core of the M. D. Anderson Cancer Center Prostate SPORE is to expand the integration of investigators from diverse scientific disciplines who have joined the translational research effort in prostate cancer. It is the purpose of the Administrative Core to provide continuous leadership and general administrative support for all SPORE-related activities. Dr. Christopher Logothetis, Director, and Dr. Timothy Thompson, Co-Director, provide support for all SPORE research projects, cores, and programs and ensure compliance with all governmental regulations, policies, and requirements. The Administrative Core coordinates data quality control and quality assurance in conjunction with the Biostatistics and Bioinformatics and Specimen Cores and the Internal and External Advisory Boards. The Administrative Core convenes all meetings of the SPORE, including seminars and lectures presented by scientific leaders in basic, translational, and clinical prostate cancer research brought to the SPORE by the Directors. With the Program Directors, the Administrative Core monitors the selection of projects and trainees for the Developmental Research and Career Development Programs, respectively. Dr. Logothetis chairs the Executive Committee, composed ofthe Co-Principal Investigator and senior scientific leaders with extensive SPORE experience. To address the ongoing needs of the minority and medically underserved communities in Houston and Harris County, Texas, Dr. Curtis Pettaway (Collaborator) has developed the Prostate Outreach Program integrated into SPORE research through the Administrative Core. Special Contributor Dr. Randall Millikan has developed the M. D. Anderson Prostate Research database (Research Repository) which serves the increasing data and bioinformatics needs of SPORE investigators, in collaboration with the Biostatistics and Bioinformatics and Specimen Cores. The Patient Advocacy program brings patient representation to the SPORE and increases awareness and education of prostate cancer research, treatment, and prevention in the community.
The principal role of the Administrative Core of the M. D. Anderson Cancer Center Prostate SPORE is to expand the integration of investigators from diverse scientific disciplines who have joined the translational research effort in prostate cancer, and to provide continuous leadership and general administrative support for all SPORE-related activities.
|Jin, J-K; Tien, P-C; Cheng, C-J et al. (2015) Talin1 phosphorylation activates ?1 integrins: a novel mechanism to promote prostate cancer bone metastasis. Oncogene 34:1811-21|
|Han, Ying; Signorello, Lisa B; Strom, Sara S et al. (2015) Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer 136:1210-7|
|Yu, Guoyu; Lee, Yu-Chen; Cheng, Chien-Jui et al. (2015) RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res 13:348-57|
|Al Olama, Ali Amin; Kote-Jarai, Zsofia; Berndt, Sonja I et al. (2014) A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet 46:1103-9|
|Satcher, Robert L; Pan, Tianhong; Cheng, Chien-Jui et al. (2014) Cadherin-11 in renal cell carcinoma bone metastasis. PLoS One 9:e89880|
|Jiang, Xianhan; Li, Xun; Huang, Hai et al. (2014) Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer. Cancer 120:1228-36|
|Tien, Jean Ching-Yi; Liao, Lan; Liu, Yonghong et al. (2014) The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. Int J Biol Sci 10:1116-27|
|Li, Likun; Chang, Wenjun; Yang, Guang et al. (2014) Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer. Sci Signal 7:ra47|
|Li, Hongge; Tao, Chenqi; Cai, Zhigang et al. (2014) Frs2* and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci 127:571-82|
|Lin, Zhuo-Yuan; Huang, Ya-Qiang; Zhang, Yan-Qiong et al. (2014) MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1. Int J Cancer 135:541-50|
Showing the most recent 10 out of 77 publications