The Lung Cancer Disparities Center will be an interdisciplinary center for research (including community based participatory research), core support and dissemination activities focused on understanding and altering the determinants of racial/ethnic and socioeconomic status (SES) disparities along the continuum of lung cancer. Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations;without cigarette smoking, lung cancer would be rare. Thus, identifying effective strategies to prevent the initiation of smoking and facilitate cessation among smokers is critical to reducing the risk of lung cancer. We also need to better understand the contribution of the social environment to the onset, course, and outcomes of lung cancer. The five projects and cores have the following specific aims: 1) develop and test novel tobacco control interventions that address the social context that initiate and sustain smoking behavior;2) develop and apply sophisticated concepts, measures, and methods regarding community-focused research to all of the activities of Center;3) draw on the expertise of a multidisciplinary team of researchers to bring a social determinants perspective to the clinical factors and other individual level factors that lead to social disparities in lung cancer survival and the genetic factors that could affect the onset, course and outcomes of lung cancer;4) refine existing conceptual and methodological approaches to understanding and describing the joint contribution of race/ethnicity and SES to lung cancer;5) develop a strong and cutting-edge training program to train the population health investigators of the future;and 6) fund highly innovative and high-risk pilot projects to inform research and application concerned with jointly understanding race/ethnicity and SES to disparities in lung cancer and its determinants. Significantly, this work will be accomplished by a transdisciplinary team of researchers who have made seminal contributions to population health and health disparities, in an institutional environment in which there is substantial intellectual and financial support for such an interdisciplinary Center.

Public Health Relevance

The Center on Lung Cancer Disparities will identify how environmental conditions - related to race/ethnicity and patterns of risk produce social disparities in lung cancer outcomes by influencing multiple pathways leading to poor health. Our Center focuses on one specific condition (lung cancer) and its key behavioral determinant (cigarette smoking). Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations;without cigarette smoking, lung cancer would be rare.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center (P50)
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Special Emphasis Panel (ZCA1-SRLB-3 (J1))
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Srinivasan, Shobha
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Harvard University
Social Sciences
Schools of Public Health
United States
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Blanton, Hart; Snyder, Leslie B; Strauts, Erin et al. (2014) Effect of graphic cigarette warnings on smoking intentions in young adults. PLoS One 9:e96315
Duncan, Dustin T; Kawachi, Ichiro; Melly, Steven J et al. (2014) Demographic disparities in the tobacco retail environment in Boston: a citywide spatial analysis. Public Health Rep 129:209-15
Duncan, Dustin T; Kawachi, Ichiro; Subramanian, S V et al. (2014) Examination of how neighborhood definition influences measurements of youths' access to tobacco retailers: a methodological note on spatial misclassification. Am J Epidemiol 179:373-81
John, Dolly A; Kawachi, Ichiro; Lathan, Christopher S et al. (2014) Disparities in perceived unmet need for supportive services among patients with lung cancer in the Cancer Care Outcomes Research and Surveillance Consortium. Cancer 120:3178-91
Slopen, Natalie; Williams, David R (2014) Discrimination, other psychosocial stressors, and self-reported sleep duration and difficulties. Sleep 37:147-56
Kontos, Emily; Blake, Kelly D; Chou, Wen-Ying Sylvia et al. (2014) Predictors of eHealth usage: insights on the digital divide from the Health Information National Trends Survey 2012. J Med Internet Res 16:e172
Nagler, Rebekah H; Viswanath, Kasisomayajula (2013) Implementation and research priorities for FCTC Articles 13 and 16: tobacco advertising, promotion, and sponsorship and sales to and by minors. Nicotine Tob Res 15:832-46
John, Dolly A; Williams, David R (2013) Mental health service use from a religious or spiritual advisor among Asian Americans. Asian J Psychiatr 6:599-605
Slopen, Natalie; Kontos, Emily Z; Ryff, Carol D et al. (2013) Psychosocial stress and cigarette smoking persistence, cessation, and relapse over 9-10 years: a prospective study of middle-aged adults in the United States. Cancer Causes Control 24:1849-63
Linder, Jeffrey A; Rigotti, Nancy A; Brawarsky, Phyllis et al. (2013) Use of practice-based research network data to measure neighborhood smoking prevalence. Prev Chronic Dis 10:E84

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