Core A- The Administrative Core, will provide for overall direction, coordination, and administration of the Case Gl SPORE. The Administrative Core will include: The SPORE Principal Investigator, the SPORE Co- Principal Investigator, and the SPORE Administrative Coordinator. The Administrative Core will oversee the functioning of: the SPORE Executive Committee, the SPORE Internal Advisory Board, the SPORE External Advisory Board, and the SPORE Patient Advocates Advisory Board. Responsibilities of the Administrative Core will include: ? Oversee conduct of all SPORE activities; ? Oversee administration and coordination of Core Facility utilization and accounting; ? Oversee quality control and quality improvement processes for core facilities; ? Oversee management and accounting of grant funds;assure monthly reconciliation of all accounts; ? Assure compliance and maintain documents for all institutional regulatory requirements for human experimentation, animal utilization, toxic material and safety training and utilization; ? Ensure compliance and coordination with all reporting regulations; ? Ensure compliance with all requirements for research progress reports; ? Manage all intellectual property affairs arising from SPORE-sponsored research; ? Coordinate SPORE seminars and retreats; ? Convene regular meetings of Steering Committee; ? Organize annual visits of External Advisory Committee; ? Coordinate solicitation and evaluation of pilot research studies; ? Coordinate solicitation and evaluation of career development awards; ? Represent the SPORE in interactions with other Centers, Departments, the School of Medicine, affiliated hospitals and community organizations; ? Coordinate and assure participation of the Case Gl SPORE in National SPORE meetings.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA150964-03
Application #
8567135
Study Section
Special Emphasis Panel (ZCA1-RPRB-M)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
3
Fiscal Year
2013
Total Cost
$180,256
Indirect Cost
$62,535
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Yu, Ming; Maden, Sean K; Stachler, Matthew et al. (2018) Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis. Gut :
Berger, Nathan A (2018) New light on the pancreatic cyst conundrum. Transl Cancer Res 7:S545-S548
Sarvestani, Samaneh K; Signs, Steven A; Lefebvre, Veronique et al. (2018) Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids. Oncotarget 9:28717-28730
Berger, Nathan A (2018) Young Adult Cancer: Influence of the Obesity Pandemic. Obesity (Silver Spring) 26:641-650
Moinova, Helen R; LaFramboise, Thomas; Lutterbaugh, James D et al. (2018) Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus. Sci Transl Med 10:
Cooper, Gregory S; Markowitz, Sanford D; Chen, Zhengyi et al. (2018) Performance of multitarget stool DNA testing in African American patients. Cancer 124:3876-3880
Berger, Nathan A; Scacheri, Peter C (2018) Targeting Epigenetics to Prevent Obesity Promoted Cancers. Cancer Prev Res (Phila) 11:125-128
Cooper, Gregory S; Markowitz, Sanford D; Chen, Zhengyi et al. (2018) Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing. Dig Dis Sci 63:1449-1453
Somasundaram, Saigopal; Forrest, Megan E; Moinova, Helen et al. (2018) The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer. Clin Epigenetics 10:127
Codipilly, Don Chamil; Chandar, Apoorva Krishna; Singh, Siddharth et al. (2018) The Effect of Endoscopic Surveillance in Patients With Barrett's Esophagus: A Systematic Review and Meta-analysis. Gastroenterology 154:2068-2086.e5

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