Core A- The Administrative Core, will provide for overall direction, coordination, and administration of the Case Gl SPORE. The Administrative Core will include: The SPORE Principal Investigator, the SPORE Co- Principal Investigator, and the SPORE Administrative Coordinator. The Administrative Core will oversee the functioning of: the SPORE Executive Committee, the SPORE Internal Advisory Board, the SPORE External Advisory Board, and the SPORE Patient Advocates Advisory Board. Responsibilities of the Administrative Core will include: ? Oversee conduct of all SPORE activities; ? Oversee administration and coordination of Core Facility utilization and accounting; ? Oversee quality control and quality improvement processes for core facilities; ? Oversee management and accounting of grant funds;assure monthly reconciliation of all accounts; ? Assure compliance and maintain documents for all institutional regulatory requirements for human experimentation, animal utilization, toxic material and safety training and utilization; ? Ensure compliance and coordination with all reporting regulations; ? Ensure compliance with all requirements for research progress reports; ? Manage all intellectual property affairs arising from SPORE-sponsored research; ? Coordinate SPORE seminars and retreats; ? Convene regular meetings of Steering Committee; ? Organize annual visits of External Advisory Committee; ? Coordinate solicitation and evaluation of pilot research studies; ? Coordinate solicitation and evaluation of career development awards; ? Represent the SPORE in interactions with other Centers, Departments, the School of Medicine, affiliated hospitals and community organizations; ? Coordinate and assure participation of the Case Gl SPORE in National SPORE meetings.

National Institute of Health (NIH)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Case Western Reserve University
United States
Zip Code
Chak, Amitabh; Buttar, Navtej S; Foster, Nathan R et al. (2015) Metformin does not reduce markers of cell proliferation in esophageal tissues of patients with Barrett's esophagus. Clin Gastroenterol Hepatol 13:665-72.e1-4
Sanchis-Gomar, Fabian; Lucia, Alejandro; Yvert, Thomas et al. (2015) Physical inactivity and low fitness deserve more attention to alter cancer risk and prognosis. Cancer Prev Res (Phila) 8:105-10
Luo, Yanxin; Wong, Chao-Jen; Kaz, Andrew M et al. (2014) Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology 147:418-29.e8
Fink, Stephen P; Yamauchi, Mai; Nishihara, Reiko et al. (2014) Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). Sci Transl Med 6:233re2
Koon, Henry B; Krown, Susan E; Lee, Jeannette Y et al. (2014) Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042. J Clin Oncol 32:402-8
Corradin, Olivia; Saiakhova, Alina; Akhtar-Zaidi, Batool et al. (2014) Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Res 24:1-13
Hao, Yujun; Zhao, Shuliang; Wang, Zhenghe (2014) Targeting the protein-protein interaction between IRS1 and mutant p110* for cancer therapy. Toxicol Pathol 42:140-7
Cummings 3rd, Kenneth C; Patel, Meatal; Htoo, Phyo Than et al. (2014) A comparison of the effects of epidural analgesia versus traditional pain management on outcomes after gastric cancer resection: a population-based study. Reg Anesth Pain Med 39:200-7
Alashkar, Bronia; Faulx, Ashley L; Hepner, Ashley et al. (2014) Development of a program to train physician extenders to perform transnasal esophagoscopy and screen for Barrett's esophagus. Clin Gastroenterol Hepatol 12:785-92
Scott, Anthony; Song, Jing; Ewing, Rob et al. (2014) Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications. Acta Biochim Biophys Sin (Shanghai) 46:199-203

Showing the most recent 10 out of 32 publications