The overall objective of the Case Gl SPORE Career Development Program (SCDP) is to develop the next generation of Gl Cancer Translational Scholars who are 1) trained in the broad fundamentals of Gl cancer pathobiology;2) ready to lead an independent translational Gl cancer research program;3) oriented and able to most effectively utilize innovative translational and transdisciplinary science approaches to attack and solve problems associated with Gl malignancies;4) committed to improving all aspects of patient health relevant to Gl malignancies across the spectrum from etiology through prevention, screening, diagnosis, therapy and survivorship, and 5) prepared with sufficient understanding of academic policies and institutional, community and national resources to most effectively support program development and promote academic advancement. The Gl SCDP builds on a strong track record of preparing trainees for successful careers in Gl Cancer Care and Research will support up to 4 SCDP Scholars per year with funds provided from the SPORE Grant, the Case Comprehensive Cancer Center and its NCI sponsored K12 award. Opportunities for translational research training will be provided in collaboration with the CWRU and Clinical Translational Science Award (CTSA) - KL2 Career Development Program. Scholars will be provided with 75% protected time for research and career training. The training program will consist of 4 main core components: 1) Research Project;2) Research Training;3) Multidisciplinary Mentoring and 4) Structured Research and Career Development Planning. Each scholar will be provided with a team of 3 mentors including 1) a Research Project Mentor, 2) a Translational Research Mentor, and 3) a Career Development Mentor to guide the scholars to develop successful research and academic careers focused on translational Gl Cancer Research. Scholars progress and performance and that of the overall program will be monitored by the SCDP Scholars Council and scholars will be recruited on both a national and local level with special efforts made to recruit women and members of underrepresented ethnic groups.

Public Health Relevance

The Case Gl SPORE Career Development Program will provide a series of 2 year career training opportunities to prepare investigators for careers in translational Gl Cancer research. Selected applicants will have 75% protected time for research and training and will conduct a mentored research project with oversight provided by a research mentor, a translational mentor and a career development mentor.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA150964-04
Application #
8711352
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Desai, Amar; Zhang, Yongyou; Park, Youngsoo et al. (2018) A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support. Haematologica 103:1054-1064
Chan, M Q; Blum, A E; Chandar, A K et al. (2018) Association of sporadic and familial Barrett's esophagus with breast cancer. Dis Esophagus 31:
Cummings III, Kenneth C; Zimmerman, Nicole M; Maheshwari, Kamal et al. (2018) Epidural compared with non-epidural analgesia and cardiopulmonary complications after colectomy: A retrospective cohort study of 20,880 patients using a national quality database. J Clin Anesth 47:12-18
Guo, Xuan; Zhao, Yiqing; Nguyen, Hieu et al. (2018) Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay. J Vis Exp :
Yu, Ming; Maden, Sean K; Stachler, Matthew et al. (2018) Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis. Gut :
Berger, Nathan A (2018) New light on the pancreatic cyst conundrum. Transl Cancer Res 7:S545-S548
Sarvestani, Samaneh K; Signs, Steven A; Lefebvre, Veronique et al. (2018) Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids. Oncotarget 9:28717-28730
Berger, Nathan A (2018) Young Adult Cancer: Influence of the Obesity Pandemic. Obesity (Silver Spring) 26:641-650
Moinova, Helen R; LaFramboise, Thomas; Lutterbaugh, James D et al. (2018) Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus. Sci Transl Med 10:
Cooper, Gregory S; Markowitz, Sanford D; Chen, Zhengyi et al. (2018) Performance of multitarget stool DNA testing in African American patients. Cancer 124:3876-3880

Showing the most recent 10 out of 141 publications