Dr. Snyder will provide overall direction of the center comprising scientific, financial and administrative perspectives. He will be responsible for determining the intellectual direction of the program and for making appropriate changes when necessary. Administrative, scientific and financial functions he will address will include preparation of scientific progress reports and renewals, coordination and direction of research projects and their integration, and consultation with internal and external advisory committees as well as outside consultants. He will also be responsible for allocating budgets and organizing seminars and meetings related to the Center grant, justifying expenditures and handling all records and finances for the project. Snyder has served as center director throughout the 40 years of the center's existence and thus has substantial experience in successfully coordinating the research of Pis and ensuring high scientific standards. Snyder devotes at least 40% of his effort to the research and administrative activities of this grant with 20% devoted to center administration. In practice, generally more than half of his research time is devoted to the activities of the Center. Barbara Ziegler will serve as the administrative coordinator, handling the implementation of many of the functions described above. She will also prepare manuscripts, progress reports and correspondence. Additionally, she will serve as financial administrator of the project, maintaining records of all financial transactions. Ms. Ziegler has over ten years of experience in executing these functions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA000266-43
Application #
8663843
Study Section
Special Emphasis Panel (ZDA1-EXL-T)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
43
Fiscal Year
2014
Total Cost
$1,395,760
Indirect Cost
$534,180
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Harraz, Maged M; Snyder, Solomon H (2017) Antidepressant Actions of Ketamine Mediated by the Mechanistic Target of Rapamycin, Nitric Oxide, and Rheb. Neurotherapeutics 14:728-733
Park, Alan Jung; Havekes, Robbert; Fu, Xiuping et al. (2017) Learning induces the translin/trax RNase complex to express activin receptors for persistent memory. Elife 6:
Fu, Chenglai; Xu, Jing; Cheng, Weiwei et al. (2017) Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via ?-actinin and focal adhesion kinase. Proc Natl Acad Sci U S A 114:2036-2041
Paul, Bindu D; Snyder, Solomon H (2017) Gasotransmitter hydrogen sulfide signaling in neuronal health and disease. Biochem Pharmacol :
Dawson, Ted M; Dawson, Valina L (2017) Mitochondrial Mechanisms of Neuronal Cell Death: Potential Therapeutics. Annu Rev Pharmacol Toxicol 57:437-454
Fu, Xiuping; Shah, Aparna; Baraban, Jay M (2016) Rapid reversal of translational silencing: Emerging role of microRNA degradation pathways in neuronal plasticity. Neurobiol Learn Mem 133:225-232
Mata, Ignacio F; Leverenz, James B; Weintraub, Daniel et al. (2016) GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease. Mov Disord 31:95-102
Rosenthal, Liana S; Drake, Daniel; Alcalay, Roy N et al. (2016) The NINDS Parkinson's disease biomarkers program. Mov Disord 31:915-23
Mills, Kelly A; Mari, Zoltan; Bakker, Catherine et al. (2016) Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients. Parkinsonism Relat Disord 33:102-106
Xu, Jin-Chong; Fan, Jing; Wang, Xueqing et al. (2016) Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med 8:333ra48

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