As all Center components will use genetically engineered mice, a central Animal Breeding Core (AB Core) will be used to meet the animal needs of all Center projects. The AB-Core was established in the previous funding cycle and developed a set of standardized procedures to accomplish this goal.
The aims of the AB-Core are as follows: 1. The AB-Core will co-ordinate with each component to provide the required cohorts of mice as needed. 2. The AB-Core will maintain each line under optimal breeding management practices. 3. As many components will utilize cross-bred lines, the AB-Core will ensure all lines are correctly maintained as congenic on the C57BL/6J background. 4. The AB-Core will follow the correct breeding strategies to ensure wild type and mutant mice are bred as littermates. 5. The AB-Core will verify that correct patterns of expression are achieved following cre- mediated deletion in both males and females.
|Xu, Ji; Bernstein, Alexander M; Wong, Angela et al. (2016) P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. J Neurosci 36:8902-20|
|Walwyn, Wendy M; Chen, Wenling; Kim, Hyeyoung et al. (2016) Sustained Suppression of Hyperalgesia during Latent Sensitization by Î¼-, Î´-, and Îº-opioid receptors and Î±2A Adrenergic Receptors: Role of Constitutive Activity. J Neurosci 36:204-21|
|Storey, Granville P; Gonzalez-Fernandez, Gabriel; Bamford, Ian J et al. (2016) Nicotine Modifies Corticostriatal Plasticity and Amphetamine Rewarding Behaviors in Mice(1,2,3). eNeuro 3:|
|Boulos, Laura-Joy; Darcq, Emmanuel; Kieffer, Brigitte Lina (2016) Translating the Habenula-From Rodents to Humans. Biol Psychiatry :|
|Wassum, Kate M; Greenfield, Venuz Y; Linker, Kay E et al. (2016) Inflated reward value in early opiate withdrawal. Addict Biol 21:221-33|
|Taylor, Anna M W; Castonguay, Annie; Ghogha, Atefeh et al. (2016) Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology 41:949-59|
|Erbs, E; Faget, L; Ceredig, R A et al. (2016) Impact of chronic morphine on delta opioid receptor-expressing neurons in the mouse hippocampus. Neuroscience 313:46-56|
|Mendez, Ian A; Maidment, Nigel T; Murphy, Niall P (2016) Parsing the hedonic and motivational influences of nociceptin on feeding using licking microstructure analysis in mice. Behav Pharmacol 27:516-27|
|Becker, JÃ©rÃ´me A J; Kieffer, Brigitte L; Le Merrer, Julie (2016) Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol. Addict Biol :|
|Pradhan, Amynah A; Perroy, Julie; Walwyn, Wendy M et al. (2016) Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function. J Neurosci 36:3541-51|
Showing the most recent 10 out of 94 publications