As all Center components will use genetically engineered mice, a central Animal Breeding Core (AB Core) will be used to meet the animal needs of all Center projects. The AB-Core was established in the previous funding cycle and developed a set of standardized procedures to accomplish this goal.
The aims of the AB-Core are as follows: 1. The AB-Core will co-ordinate with each component to provide the required cohorts of mice as needed. 2. The AB-Core will maintain each line under optimal breeding management practices. 3. As many components will utilize cross-bred lines, the AB-Core will ensure all lines are correctly maintained as congenic on the C57BL/6J background. 4. The AB-Core will follow the correct breeding strategies to ensure wild type and mutant mice are bred as littermates. 5. The AB-Core will verify that correct patterns of expression are achieved following cre- mediated deletion in both males and females.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA005010-27
Application #
8501392
Study Section
Special Emphasis Panel (ZDA1-EXL-T)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
27
Fiscal Year
2013
Total Cost
$204,928
Indirect Cost
$71,858
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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