The Statistics Core has five specific aims essential to achieving the Center's mission. This Core serves the Center's multifaceted needs by 1) designing and administering CEDAR's Management and Information System regulating the a) Subject Tracking Information System;b) Research Protocol Information System (collection, entry, verification, storage, scoring, backup, security and confidentiality, retrieval, processing and;disseminating of the data), and c) the Local Area Network (LAN) and CEDAR's Web Site;. 2) conducting psychometric analyses of all instruments used in CEDAR to assure their quality;3) investigating the robustness of item response theory (IRT) methods pertinent to longitudinal family research (e.g., missing data, dependency between items, heterogeneity of the sample);4) leading the CEDAR faculty engaged in analyses directed at confirming/disconfirming CEDAR's biopsychosocial theory of SUD etiology;and, 5) providing consultative statistical support for CEDAR faculty, fellows, and students, in addition, all statistical analyses contained, in data-based manuscripts are reviewed by this Core prior to submission for publication.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Specialized Center (P50)
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Special Emphasis Panel (ZDA1-EXL-T)
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University of Pittsburgh
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Shaffer, John R; Carlson, Jenna C; Stanley, Brooklyn O C et al. (2015) Effects of enamel matrix genes on dental caries are moderated by fluoride exposures. Hum Genet 134:159-67
Hasler, Brant P; Soehner, Adriane M; Clark, Duncan B (2015) Sleep and circadian contributions to adolescent alcohol use disorder. Alcohol 49:377-87
Ridenour, Ty A; Halliburton, Amanda E; Bray, Bethany C (2015) Does DSM-5 nomenclature for inhalant use disorder improve upon DSM-IV? Psychol Addict Behav 29:211-7
Hasler, Brant P; Soehner, Adriane M; Clark, Duncan B (2014) Circadian rhythms and risk for substance use disorders in adolescence. Curr Opin Psychiatry 27:460-6
Tarter, Ralph; Kirisci, Levent; Reynolds, Maureen (2014) A new approach to researching the etiology of cannabis use disorder: integrating transmissible and nontransmissible risk within a developmental framework. Subst Abus 35:336-43
Kirillova, Galina; Reynolds, Maureen; Kirisci, Levent et al. (2014) Familiality of addiction and its developmental mechanisms in girls. Drug Alcohol Depend 143:213-8
Parker, Andrew M; Stone, Eric R (2014) Identifying the Effects of Unjustified Confidence versus Overconfidence: Lessons Learned from Two Analytic Methods. J Behav Decis Mak 27:134-145
Clark, Duncan B; de Wit, Harriet; Iacono, William G (2014) ADHD, impulsivity and alcohol abuse: methods, results, and implications. Exp Clin Psychopharmacol 22:141-3
Blanco, Carlos; Rafful, Claudia; Wall, Melanie M et al. (2014) Towards a comprehensive developmental model of cannabis use disorders. Addiction 109:284-94
Zhai, Zu Wei; Kirisci, Levent; Tarter, Ralph E et al. (2014) Psychological dysregulation during adolescence mediates the association of parent-child attachment in childhood and substance use disorder in adulthood. Am J Drug Alcohol Abuse 40:67-74

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