The overall goal of the UT Houston Substance Abuse Research-Medication Development Center (SARMDC) is to develop safe and effective medications for cocaine dependence through the study of the behavioral and neurochemical mechanisms associated with the promising initial findings of replacement therapy. The Administrative Core will promote this goal by serving as a general resource for other projects and the Advanced Clinical Design &Statistical Methodology Core.
The Specific Aims of the Administrative core are listed below:
Aim 1. To provide infrastructure support for clinical trials issues, including: a) subject recruitment and screening b) urine toxicology testing, c) ensuring subject confidentiality and compliance with IRB and HIPPA requirements and regulations d) documenting clinical trials on clinicaltrials.gov. e) oversight of data sharing with NIDA.
Aim 2. To provide support for Training and Education, including recruitment, supervision, and evaluation of trainees affiliated with the center.
Aim 3. To provide Fiscal and Management support, including support for pilot studies, budgetary oversight, and management of research staff.
Aim 4. To serve as the Liaison between the center and outside entities including the Department of Psychiatry, the UT Health Sciences Center, the Center for Clinical Translational Science of the University of Texas Health Science Center at Houston, the scientific advisory board, collaborating entities including addiction researchers at Baylor College of Medicine and University of Texas Medical Branch (UTMB) in Galveston, as well as NIDA.
The administrative core of the UT Houston Substance Abuse Research-Medication Development Center (SAR-MDC) will promote the goal of the center, to gain a greater understanding of the basic neurobiology of cocaine dependence in order to develop safe and effective treatments of the disorder, by providing infrastructure for clinical trials, training and education, and fiscal managerial support for the projects of the center
|Sharma, Jyoti; Rathnayaka, Nuvan; Green, Charles et al. (2016) Bradycardia as a Marker of Chronic Cocaine Use: A Novel Cardiovascular Finding. Behav Med 42:1-8|
|Vujanovic, Anka A; Rathnayaka, Nuvan; Amador, Christina D et al. (2016) Distress Tolerance: Associations With Posttraumatic Stress Disorder Symptoms Among Trauma-Exposed, Cocaine-Dependent Adults. Behav Modif 40:120-43|
|Azadeh, Shabnam; Hobbs, Brian P; Ma, Liangsuo et al. (2016) Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence. Neuroimage 125:813-24|
|Vujanovic, Anka A; Wardle, Margaret C; Liu, Shijing et al. (2016) Attentional bias in adults with cannabis use disorders. J Addict Dis 35:144-53|
|Ramesh, Divya; Keyser-Marcus, Lori A; Ma, Liangsuo et al. (2015) Prevalence of traumatic brain injury in cocaine-dependent research volunteers. Am J Addict 24:341-7|
|Stotts, Angela L; Vujanovic, Anka; Heads, Angela et al. (2015) The role of avoidance and inflexibility in characterizing response to contingency management for cocaine use disorders: A secondary profile analysis. Psychol Addict Behav 29:408-13|
|Alcorn 3rd, Joseph L; Rathnayaka, Nuvan; Swann, Alan C et al. (2015) Effects of Intranasal Oxytocin on Aggressive Responding in Antisocial Personality Disorder. Psychol Rec 65:691-703|
|Stotts, Angela L; Northrup, Thomas F (2015) The Promise of Third-Wave Behavioral Therapies in the Treatment of Substance Use Disorders. Curr Opin Psychol 2:75-81|
|Ma, Liangsuo; Steinberg, Joel L; Cunningham, Kathryn A et al. (2015) Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls. Neuroimage Clin 7:837-47|
|Dias, Nadeeka R; Lane, Scott D; Rathnayaka, Nuvan et al. (2015) Demographic and psychological factors associated with lifetime cocaine use: An exploratory factor analysis of baseline questionnaires. Addict Disord Their Treat 14:70-77|
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