The Administrative Core (Component #1) of the Methamphetamine Abuse research Center (MARC) contains the centralized administrative functions for all 3 Scientific Components (#7-9), as well as for all of the support cores (#1-6), including the Biostatistics (#2), Animal (#3), Education (#4), Translational Service (#5), and Pilot Projects (#6) Cores. The Administrative Core coordinates the scientific oversight provided by the Scientific Advisory Board, including review of Pilot Projects, and educational enrichment as provided by such activities as workshops. Executive decisions regarding MARC activities will be made by the MARC Executive Committee of Scientific and Core Component Pis. The Executive Committee will continuously evaluate progress toward general scientific research goals, and will oversee quality control mechanisms in all areas of Center activity. Additionally, administrative support will be provided for animal production (selection), genetics, statistical analyses both within and across components, educational enrichment and training, human and animal imaging studies and tissue work. Oversight will be provided for centralized core facilities characterizing and assaying human and animal samples. It will oversee genetics, bioinformatics and data sharing, biostatistical analyses, and training and educational enrichment and outreach activities. Finally, the Administrative Core will coordinate Pilot Project solicitation, review and award. Thus, the Administrative Core is structured to address two specific aims.
Specific Aim 1 : The Core provides administrative and budgetary oversight and the general coordination of all Center activities, and Specific Aim 2: The Core coordinates communication among Center investigators via a secured shared drive on the University network, and the dissemination of information to outside entities, including other investigators and Centers, via the MARC web site. The general administrative coordination of all Center activities and the Center's budget will be supervised by Dr. Janowsky, the Center Director. The coordination of and future planning for scientific directions will be supervised by Dr. Phillips, the Scientific Director, who will act as Director in Dr. Janowsky's absence.

Public Health Relevance

Administrative activities are designed to produce coordinated advances on all research fronts, facilitating discovery. Through the Education and Outreach activities ofthe Center, discoveries are disseminated to the general public.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA018165-07
Application #
8538914
Study Section
Special Emphasis Panel (ZDA1-EXL-T)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
7
Fiscal Year
2013
Total Cost
$130,443
Indirect Cost
$26,686
Name
Oregon Health and Science University
Department
Type
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Szumlinski, Karen K; Lominac, Kevin D; Campbell, Rianne R et al. (2016) Methamphetamine Addiction Vulnerability: The Glutamate, the Bad, and the Ugly. Biol Psychiatry :
Li, Minghua; Underhill, Suzanne M; Reed, Cheryl et al. (2016) Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons. Neuropsychopharmacology :
Lominac, Kevin D; Quadir, Sema G; Barrett, Hannah M et al. (2016) Prefrontal glutamate correlates of methamphetamine sensitization and preference. Eur J Neurosci 43:689-702
Loftis, Jennifer M; Lim, Miranda M (2016) Sleep disturbance in substance use disorders and comorbid chronic viral infections. Addiction 111:1093-4
Ellis, Carilyn; Hoffman, William; Jaehnert, Sarah et al. (2016) Everyday problems with executive dysfunction and impulsivity in adults recovering from methamphetamine addiction. Addict Disord Their Treat 15:1-5
Kim, Hyunjee; Hartung, Daniel M; Jacob, Reside L et al. (2016) The Concentration of Opioid Prescriptions by Providers and Among Patients in the Oregon Medicaid Program. Psychiatr Serv 67:397-404
Janowsky, Aaron; Tosh, Dilip K; Eshleman, Amy J et al. (2016) Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine. J Pharmacol Exp Ther 357:24-35
Greenberg, G D; Huang, L C; Spence, S E et al. (2016) Nest building is a novel method for indexing severity of alcohol withdrawal in mice. Behav Brain Res 302:182-90
Zou, Mu-Fa; Keck, Thomas M; Kumar, Vivek et al. (2016) Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. J Med Chem 59:2973-88
Abraham, Antony D; Neve, Kim A; Lattal, K Matthew (2016) Effects of D1 receptor knockout on fear and reward learning. Neurobiol Learn Mem 133:265-73

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