The Recruitment/Screening core will oversee recmitment and screening of eligible participants for all of the human subjects studies of the center (Projects 1-3). To accomplish this goal, we will utilize our established recruitment/screening infrastructure, which comprises: 1) an advertising system entailing television, radio, internet and other media;2) a centralized telephone call answering center that: a) provides initial telephone screening of interested smokers who respond to recruitment advertisements;and b) schedules in-person medical screening sessions;and 3) a physician and three physician assistants covering our four clinical research sites, who conduct physical examinations and additional medical evaluations to implement study inclusion/exclusion criteria. Based on previous experience, this core will be able to recruit, screen and refer to the respective center project approximately 150 participants per year. This participant flow will be more than adequate to help ensure the successful completion of all human studies proposed in this application.
Cigarette smoking is the leading preventable cause of disease and death. These health risks can be reduced substantially by quitting smoking, and yet current smoking cessation treatments have limited effectiveness. By ensuring the adequate recmitment of research participants into the clinical studies of the center, more effective treatments can be developed to aid smokers in the population.
|Briggs, Scott A; Hall, Brandon J; Wells, Corinne et al. (2016) Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats. Pharmacol Biochem Behav 142:1-7|
|Hall, Brandon J; Slade, Susan; Allenby, Cheyenne et al. (2015) Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats. Neuropharmacology 99:689-95|
|Larrauri, José A; Burke, Dennis A; Hall, Brandon J et al. (2015) Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats. Psychopharmacology (Berl) 232:3009-17|
|Potenza, Marc N (2015) Commentary on: Are we overpathologizing everyday life? A tenable blueprint for behavioral addiction research. Defining and classifying non-substance or behavioral addictions. J Behav Addict 4:139-41|
|Walton, Kevin M; Abrams, David B; Bailey, William C et al. (2015) NIH electronic cigarette workshop: developing a research agenda. Nicotine Tob Res 17:259-69|
|Brody, Arthur L; McClernon, Francis Joseph (2015) Prediction of smoking cessation with treatment: the emerging contribution of brain imaging research. Neuropsychopharmacology 40:1309-10|
|Levin, Edward D; Wells, Corinne; Johnson, Joshua E et al. (2015) Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats. Eur J Pharmacol 764:30-7|
|Hall, Brandon J; Slade, Susan; Wells, Corinne et al. (2015) Bupropion-varenicline interactions and nicotine self-administration behavior in rats. Pharmacol Biochem Behav 130:84-9|
|Cousins, Vanessa; Rose, Jed E; Levin, Edward D (2014) IV nicotine self-administration in rats using a consummatory operant licking response: sensitivity to serotonergic, glutaminergic and histaminergic drugs. Prog Neuropsychopharmacol Biol Psychiatry 54:200-5|
|Rose, Jed E; Behm, Frédérique M (2014) Combination treatment with varenicline and bupropion in an adaptive smoking cessation paradigm. Am J Psychiatry 171:1199-205|
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