Once adolescents have begun to experiment with alcohol and other drugs;and particularly when that experimentation escalates, parents are not prepared to handle the serious and complex Issues which so regularly occur. Thanks to NIDA sponsored research, there are now potent, evidence-based Interventions that could be useful to parents in these situations - if they were translated and communicated appropriately. To address this problem we are proposing a Parents'Translational Research Center that will bring an experienced, multidisciplinary team of researchers, communications experts, scientific advisors and parents themselves to adapt, evaluate and communicate these translated interventions directly to parents - without sacrificing the original principles of care or the therapeutic approach. This work simply could not be done by a single investigator, or by a single laboratory. The P50 mechanism offers an ideal opportunity to join the scientists who originated carefully selected evidence-based interventions with translational researchers (from TRI), researchers from other relevant disciplines (from the Science Advisory Board), specialists in communications, marketing and messaging (from the Partnership for a Drug Free America);and with experienced parents themselves (from the Parent Advisory Board). This team will integrate and synergize their individual talents to address the Center's organizing theme: translating key elements of proven clinical interventions into practical tools parents can use to address the substance use problems of their adolescents. The proposed Center will use a translation-informed approach (See NIH Roadmap) to focus on three questions Identified from interviews with thousands of parents facing substance abuse challenges with their adolescents: Project 1 (Winters, PI) will adapt and test a parent-focused version of a brief intervention for parents when they discover active substance use by their adolescent;Project 2 (McLellan, PI) will develop and test a Consumer Guide to adolescent treatment that will provide objective, comparative information on evidence-based practices available in community treatment programs;Project 3 (Kirby, PI) will adapt and test a parent-focused version of a behavioral intervention (CRAFT) to help parents engage and motivate treatment-resistant adolescents.

Public Health Relevance

The research is relevant to NIDA's mission to bring evidence-based knowledge, interventions and tools into broad use to solve the public health issues associated with adolescent substance abuse. CENTER CHARACTERISTICS:

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Specialized Center (P50)
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Application #
Study Section
Special Emphasis Panel (ZDA1-EXL-T (11))
Program Officer
Chambers, Jessica Campbell
Project Start
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Budget Start
Budget End
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Fiscal Year
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Treatment Research Institute, Inc. (TRI)
United States
Zip Code
Winters, Ken C; Lee, Susanne; Botzet, Andria et al. (2014) One-year outcomes and mediators of a brief intervention for drug abusing adolescents. Psychol Addict Behav 28:464-74
Hudson, Clifton R; Kirby, Kimberly C; Clements, Nicolle T et al. (2014) Social adjustment of women with and without a substance-abusing partner. J Psychoactive Drugs 46:106-13
Kaynak, Övgü; Winters, Ken C; Cacciola, John et al. (2014) Providing alcohol for underage youth: what messages should we be sending parents? J Stud Alcohol Drugs 75:590-605
Washio, Yukiko; Fairfax-Columbo, Jaymes; Ball, Emily et al. (2014) A review of guidelines on home drug testing web sites for parents. J Addict Med 8:258-63
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Kaynak, Ovgu; Meyers, Kathleen; Caldeira, Kimberly M et al. (2013) Relationships among parental monitoring and sensation seeking on the development of substance use disorder among college students. Addict Behav 38:1457-63
Arria, Amelia M; Wilcox, Holly C; Caldeira, Kimberly M et al. (2013) Dispelling the myth of "smart drugs": cannabis and alcohol use problems predict nonmedical use of prescription stimulants for studying. Addict Behav 38:1643-50
Kirby, Kimberly C; Carpenedo, Carolyn M; Dugosh, Karen L et al. (2013) Randomized clinical trial examining duration of voucher-based reinforcement therapy for cocaine abstinence. Drug Alcohol Depend 132:639-45
Arria, Amelia M; Garnier-Dykstra, Laura M; Cook, Emily T et al. (2013) Drug use patterns in young adulthood and post-college employment. Drug Alcohol Depend 127:23-30
Winters, Ken C (2013) Advances in the science of adolescent drug involvement: implications for assessment and diagnosis - experience from the United States. Curr Opin Psychiatry 26:318-24

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