Abstract

Core B's primary responsibilities are to accrue a subject population;provide the clinical service for these subjects;maintain a cochlear implant patient registry;monitor postoperative residual hearing;and obtain audiologic outcome measures that will be used in the five research projects. Core B will also provide the technical and statistical support for all investigators. The five research projects are highly interdependent and interrelated. Each project depends on data generated by the others to address their specific aims, using similar patient populations to address the Clinical Research Center's overall goals. Described here are (1) extensive preoperative evaluations required for subject accrual;(2) specific populations to be studied;(3) cochlear implants to be used;(4) postoperative audiometric monitoring of residual hearing;(5) basic outcome measures of performance that will be obtained from subjects;and (6) the time-line of subject involvement. The overall statistical design, data management and technical support are also discussed. The individual projects describe the specific research questions and how each project is interactive and dependent on the others.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
2P50DC000242-26A1
Application #
8300342
Study Section
Special Emphasis Panel (ZDC1-SRB-L (42))
Project Start
Project End
Budget Start
2012-02-15
Budget End
2013-01-31
Support Year
26
Fiscal Year
2012
Total Cost
$907,915
Indirect Cost
$306,646

  Institution

Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Shearer, A Eliot; Tejani, Viral D; Brown, Carolyn J et al. (2018) In Vivo Electrocochleography in Hybrid Cochlear Implant Users Implicates TMPRSS3 in Spiral Ganglion Function. Sci Rep 8:14165
Adunka, Oliver F; Gantz, Bruce J; Dunn, Camille et al. (2018) Minimum Reporting Standards for Adult Cochlear Implantation. Otolaryngol Head Neck Surg 159:215-219
Smith, Nicholas A; McMurray, Bob (2018) Temporal Responsiveness in Mother-Child Dialogue: A Longitudinal Analysis of Children with Normal Hearing and Hearing Loss. Infancy 23:410-431
Wu, Yu-Hsiang; Stangl, Elizabeth; Chipara, Octav et al. (2018) Characteristics of Real-World Signal to Noise Ratios and Speech Listening Situations of Older Adults With Mild to Moderate Hearing Loss. Ear Hear 39:293-304
Gantz, Bruce J; Dunn, Camille C; Oleson, Jacob et al. (2018) Acoustic plus electric speech processing: Long-term results. Laryngoscope 128:473-481
Kim, Jeong-Seo; Tejani, Viral D; Abbas, Paul J et al. (2018) Postoperative Electrocochleography from Hybrid Cochlear Implant users: An Alternative Analysis Procedure. Hear Res 370:304-315
Goman, Adele M; Dunn, Camille C; Gantz, Bruce J et al. (2018) PREVALENCE OF POTENTIAL HYBRID AND CONVENTIONAL COCHLEAR IMPLANT CANDIDATES BASED ON AUDIOMETRIC PROFILE. Otol Neurotol 39:515-517
Bonnard, Damien; Schwalje, Adam; Gantz, Bruce et al. (2018) Electric and acoustic harmonic integration predicts speech-in-noise performance in hybrid cochlear implant users. Hear Res 367:223-230
Pimperton, Hannah; Walker, Elizabeth A (2018) Word Learning in Children With Cochlear Implants: Examining Performance Relative to Hearing Peers and Relations With Age at Implantation. Ear Hear 39:980-991
McMurray, Bob; Ellis, Tyler P; Apfelbaum, Keith S (2018) How Do You Deal With Uncertainty? Cochlear Implant Users Differ in the Dynamics of Lexical Processing of Noncanonical Inputs. Ear Hear :

Showing the most recent 10 out of 247 publications