Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY ? CORE B Core B's primary responsibilities are to accrue a subject population; provide the clinical service for these subjects; maintain a cochlear implant (CI) research registry; monitor postoperative residual hearing; and obtain audiologic and speech perception outcome measures that will be used in the research projects. Core B will also provide the technical and statistical support for all investigators. The four research projects are highly interdependent and interrelated. Each project depends on data generated by the others to address their specific aims, using similar subject populations to address the Iowa Cochlear Implant Clinical Research Center's (ICICRC) overall goals. Described here are (1) extensive preoperative evaluations required for subject accrual; (2) specific populations to be studied; (3) CIs to be used; (4) basic audiologic and speech perception outcome measures of performance that will be obtained from subjects; and (5) the time-line of subject involvement. The overall statistical design, data management and technical support are also discussed. The individual projects describe the specific research questions and how each project is interactive and dependent on the others.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
2P50DC000242-31A1
Application #
9415699
Study Section
Special Emphasis Panel (ZDC1)
Project Start
Project End
Budget Start
2017-12-01
Budget End
2018-11-30
Support Year
31
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52246
McMurray, Bob; Farris-Trimble, Ashley; Rigler, Hannah (2017) Waiting for lexical access: Cochlear implants or severely degraded input lead listeners to process speech less incrementally. Cognition 169:147-164
Tejani, Viral D; Abbas, Paul J; Brown, Carolyn J (2017) Relationship Between Peripheral and Psychophysical Measures of Amplitude Modulation Detection in Cochlear Implant Users. Ear Hear 38:e268-e284
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Abbas, Paul J; Tejani, Viral D; Scheperle, Rachel A et al. (2017) Using Neural Response Telemetry to Monitor Physiological Responses to Acoustic Stimulation in Hybrid Cochlear Implant Users. Ear Hear 38:409-425
Shearer, A Eliot; Eppsteiner, Robert W; Frees, Kathy et al. (2017) Genetic variants in the peripheral auditory system significantly affect adult cochlear implant performance. Hear Res 348:138-142
Sjoberg, Kristin M; Driscoll, Virginia D; Gfeller, Kate et al. (2017) The impact of electric hearing on children's timbre and pitch perception and talker discrimination. Cochlear Implants Int 18:36-48
Samuelson, Larissa K; McMurray, Bob (2017) What does it take to learn a word? Wiley Interdiscip Rev Cogn Sci 8:
Oleson, Jacob J; Cavanaugh, Joseph E; McMurray, Bob et al. (2017) Detecting time-specific differences between temporal nonlinear curves: Analyzing data from the visual world paradigm. Stat Methods Med Res 26:2708-2725
Scheperle, Rachel A; Tejani, Viral D; Omtvedt, Julia K et al. (2017) Delayed changes in auditory status in cochlear implant users with preserved acoustic hearing. Hear Res 350:45-57
Brown, Carolyn J; Jeon, Eun-Kyung; Driscoll, Virginia et al. (2017) Effects of Long-Term Musical Training on Cortical Auditory Evoked Potentials. Ear Hear 38:e74-e84

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