The Microarray Core has been the engine driving much of the genomics research in the Center over the past four years. As a result of our ability to negotiate very favorable prices with the vendors by the scale of our operation and our subsidies to members of the Center made possible by the Center grant, investigators have been able to apply comparative genome hybridization and global transcription analysis to almost every project explored under the aegis of this Center grant. Moreover, they have been able to use sufficient numbers of arrays so that the data generated by these experiments have the statistical power to yield meaningful results.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM071508-09
Application #
8381484
Study Section
Special Emphasis Panel (ZGM1-CBCB-4)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
9
Fiscal Year
2012
Total Cost
$683,809
Indirect Cost
$259,081
Name
Princeton University
Department
Type
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Lee, Ha Neul; Mitra, Mithun; Bosompra, Oye et al. (2018) RECK isoforms have opposing effects on cell migration. Mol Biol Cell 29:1825-1838
Garcia, Hernan G; Gregor, Thomas (2018) Live Imaging of mRNA Synthesis in Drosophila. Methods Mol Biol 1649:349-357
Mitra, Mithun; Johnson, Elizabeth L; Swamy, Vinay S et al. (2018) Alternative polyadenylation factors link cell cycle to migration. Genome Biol 19:176
Gibney, Patrick A; Schieler, Ariel; Chen, Jonathan C et al. (2018) Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast. Mol Biol Cell 29:897-910
Mitra, Mithun; Lee, Ha Neul; Coller, Hilary A (2018) Determining Genome-wide Transcript Decay Rates in Proliferating and Quiescent Human Fibroblasts. J Vis Exp :
Lee, Andrew H; Dhingra, Satish K; Lewis, Ian A et al. (2018) Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter. Sci Rep 8:13578
Bartlett, Thomas M; Bratton, Benjamin P; Duvshani, Amit et al. (2017) A Periplasmic Polymer Curves Vibrio cholerae and Promotes Pathogenesis. Cell 168:172-185.e15
Klibaite, Ugne; Berman, Gordon J; Cande, Jessica et al. (2017) An unsupervised method for quantifying the behavior of paired animals. Phys Biol 14:015006
Sanchez, Monica R; Miller, Aaron W; Liachko, Ivan et al. (2017) Differential paralog divergence modulates genome evolution across yeast species. PLoS Genet 13:e1006585
Matheson, Kinnari; Parsons, Lance; Gammie, Alison (2017) Whole-Genome Sequence and Variant Analysis of W303, a Widely-Used Strain of Saccharomyces cerevisiae. G3 (Bethesda) 7:2219-2226

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