The two Cores of SBCNY will serve as the incubators for the development and standard usage of tools and technologies that will support the four research themes and the education and outreach activities of the Center. The cores will interact closely with one another, other Center investigators and non-Center researchers on an ongoing basis. Space limitations preclude detailed descriptions. The cores are run in a team fashion by Center investigators with deep technological expertise. Computational Core Center Investigators: Avi Ma'ayan, Marc Birtwistie, David McQueen and Eric Sobie.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM071558-07
Application #
8728882
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
7
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Lee, Young-Seon; Hwang, Minki; Song, Jun-Seop et al. (2016) The Contribution of Ionic Currents to Rate-Dependent Action Potential Duration and Pattern of Reentry in a Mathematical Model of Human Atrial Fibrillation. PLoS One 11:e0150779
Leffler, Shoshana R; Legué, Emilie; Aristizábal, Orlando et al. (2016) A Mathematical Model of Granule Cell Generation During Mouse Cerebellum Development. Bull Math Biol 78:859-78
Stern, Alan D; Rahman, Adeeb H; Birtwistle, Marc R (2016) Cell size assays for mass cytometry. Cytometry A :
Smith, Gregory R; Birtwistle, Marc R (2016) A Mechanistic Beta-Binomial Probability Model for mRNA Sequencing Data. PLoS One 11:e0157828
Byrne, Kate M; Monsefi, Naser; Dawson, John C et al. (2016) Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches. Cell Syst 2:38-48
Gallo, James M; Birtwistle, Marc R (2015) Network pharmacodynamic models for customized cancer therapy. Wiley Interdiscip Rev Syst Biol Med 7:243-51
Klinke 2nd, David J; Birtwistle, Marc R (2015) In silico model-based inference: an emerging approach for inverse problems in engineering better medicines. Curr Opin Chem Eng 10:14-24
Bastiaens, Philippe; Birtwistle, Marc R; Blüthgen, Nils et al. (2015) Silence on the relevant literature and errors in implementation. Nat Biotechnol 33:336-9
Azeloglu, Evren U; Iyengar, Ravi (2015) Good practices for building dynamical models in systems biology. Sci Signal 8:fs8
Birtwistle, Marc R (2015) Analytical reduction of combinatorial complexity arising from multiple protein modification sites. J R Soc Interface 12:

Showing the most recent 10 out of 171 publications