The two Cores of SBCNY will serve as the incubators for the development and standard usage of tools and technologies that will support the four research themes and the education and outreach activities of the Center. The cores will interact closely with one another, other Center investigators and non-Center researchers on an ongoing basis. Space limitations preclude detailed descriptions. The cores are run in a team fashion by Center investigators with deep technological expertise. Computational Core Center Investigators: Avi Ma'ayan, Marc Birtwistie, David McQueen and Eric Sobie.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM071558-07
Application #
8728882
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
7
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Jones, DeAnalisa C; Gong, Jingqi Q X; Sobie, Eric A (2018) A privileged role for neuronal Na+ channels in regulating ventricular [Ca2+] and arrhythmias. J Gen Physiol 150:901-905
Barrette, Anne Marie; Bouhaddou, Mehdi; Birtwistle, Marc R (2018) Integrating Transcriptomic Data with Mechanistic Systems Pharmacology Models for Virtual Drug Combination Trials. ACS Chem Neurosci 9:118-129
Xiong, Yuguang; Soumillon, Magali; Wu, Jie et al. (2017) A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries. Sci Rep 7:14626
Falkenberg, Cibele V; Azeloglu, Evren U; Stothers, Mark et al. (2017) Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability. PLoS Comput Biol 13:e1005433
Gong, Jingqi Q X; Shim, Jaehee V; Núñez-Acosta, Elisa et al. (2017) I love it when a plan comes together: Insight gained through convergence of competing mathematical models. J Mol Cell Cardiol 102:31-33
Hansen, Jens; Meretzky, David; Woldesenbet, Simeneh et al. (2017) A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes. Sci Rep 7:17689
Stern, Alan D; Rahman, Adeeb H; Birtwistle, Marc R (2017) Cell size assays for mass cytometry. Cytometry A 91:14-24
Stillitano, Francesca; Hansen, Jens; Kong, Chi-Wing et al. (2017) Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells. Elife 6:
Ron, Amit; Azeloglu, Evren U; Calizo, Rhodora C et al. (2017) Cell shape information is transduced through tension-independent mechanisms. Nat Commun 8:2145
Flamini, Vittoria; DeAnda, Abe; Griffith, Boyce E (2016) Immersed boundary-finite element model of fluid-structure interaction in the aortic root. Theor Comput Fluid Dyn 30:139-164

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