Abstract

Goals The overall goal of the Experimental Core is to standardize experimental procedures and data gathering in the four thematic projects so as to synchronize conditions for biochemical and physiological experiments and the high throughput experiments achieve rigorous quality control during tissue/cell preparation for high throughput experiments that will be conducted by this Core. The genomics and proteomics measurements will be conducted by this core under the supervision of Milind Mahajan and Hong Li, respectively.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM071558-07
Application #
8728884
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
7
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Jones, DeAnalisa C; Gong, Jingqi Q X; Sobie, Eric A (2018) A privileged role for neuronal Na+ channels in regulating ventricular [Ca2+] and arrhythmias. J Gen Physiol 150:901-905
Barrette, Anne Marie; Bouhaddou, Mehdi; Birtwistle, Marc R (2018) Integrating Transcriptomic Data with Mechanistic Systems Pharmacology Models for Virtual Drug Combination Trials. ACS Chem Neurosci 9:118-129
Xiong, Yuguang; Soumillon, Magali; Wu, Jie et al. (2017) A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries. Sci Rep 7:14626
Falkenberg, Cibele V; Azeloglu, Evren U; Stothers, Mark et al. (2017) Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability. PLoS Comput Biol 13:e1005433
Gong, Jingqi Q X; Shim, Jaehee V; Núñez-Acosta, Elisa et al. (2017) I love it when a plan comes together: Insight gained through convergence of competing mathematical models. J Mol Cell Cardiol 102:31-33
Hansen, Jens; Meretzky, David; Woldesenbet, Simeneh et al. (2017) A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes. Sci Rep 7:17689
Stern, Alan D; Rahman, Adeeb H; Birtwistle, Marc R (2017) Cell size assays for mass cytometry. Cytometry A 91:14-24
Stillitano, Francesca; Hansen, Jens; Kong, Chi-Wing et al. (2017) Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells. Elife 6:
Ron, Amit; Azeloglu, Evren U; Calizo, Rhodora C et al. (2017) Cell shape information is transduced through tension-independent mechanisms. Nat Commun 8:2145
Lee, Young-Seon; Hwang, Minki; Song, Jun-Seop et al. (2016) The Contribution of Ionic Currents to Rate-Dependent Action Potential Duration and Pattern of Reentry in a Mathematical Model of Human Atrial Fibrillation. PLoS One 11:e0150779

Showing the most recent 10 out of 185 publications