Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM082250-08
Application #
8727012
Study Section
Special Emphasis Panel (ZRG1-AARR-K)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
8
Fiscal Year
2014
Total Cost
$229,355
Indirect Cost
$74,240
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Davis, Zoe H; Verschueren, Erik; Jang, Gwendolyn M et al. (2015) Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Mol Cell 57:349-60
Lu, Huasong; Li, Zichong; Xue, Yuhua et al. (2014) AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation. Proc Natl Acad Sci U S A 111:E15-24
Lang, P Therese; Holton, James M; Fraser, James S et al. (2014) Protein structural ensembles are revealed by redefining X-ray electron density noise. Proc Natl Acad Sci U S A 111:237-42
Monroe, Kathryn M; Yang, Zhiyuan; Johnson, Jeffrey R et al. (2014) IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science 343:428-32
Ren, Xuefeng; Park, Sang Yoon; Bonifacino, Juan S et al. (2014) How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. Elife 3:e01754
Schulze-Gahmen, Ursula; Lu, Huasong; Zhou, Qiang et al. (2014) AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter. Elife 3:e02375
Fujinaga, Koh; Luo, Zeping; Peterlin, B Matija (2014) Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells. J Biol Chem 289:21181-90
Hu, Shenshen; Sharma, Sudhir C; Scouras, Alexander D et al. (2014) Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation. J Am Chem Soc 136:8157-60
Gable, Jonathan E; Lee, Gregory M; Jaishankar, Priyadarshini et al. (2014) Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry 53:4648-60
Holton, James M; Classen, Scott; Frankel, Kenneth A et al. (2014) The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures. FEBS J 281:4046-60

Showing the most recent 10 out of 76 publications