The Protein NMR Spectroscopy Core will focus on protein complex structure determinations, while the Nucleic Acids NMR Spectroscopy Core will focus on determining the structures of nucleic acids, RNA/protein structures, and inhibitor screening.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM082545-06
Application #
8513490
Study Section
Special Emphasis Panel (ZRG1-AARR-K (50))
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-07-31
Support Year
6
Fiscal Year
2012
Total Cost
$147,698
Indirect Cost
$48,873
Name
University of Utah
Department
Type
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Bailey, Lucas J; Sheehy, Kimberly M; Dominik, Pawel K et al. (2017) Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol :
Hammond, John A; Zhou, Li; Lamichhane, Rajan et al. (2017) A Survey of DDX21 Activity During Rev/RRE Complex Formation. J Mol Biol :
Sdano, Matthew A; Fulcher, James M; Palani, Sowmiya et al. (2017) A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife 6:
Kieffer, Collin; Ladinsky, Mark S; Ninh, Allen et al. (2017) Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography. Elife 6:
Mamede, João I; Cianci, Gianguido C; Anderson, Meegan R et al. (2017) Early cytoplasmic uncoating is associated with infectivity of HIV-1. Proc Natl Acad Sci U S A 114:E7169-E7178
Lamichhane, Rajan; Hammond, John A; Pauszek 3rd, Raymond F et al. (2017) A DEAD-box protein acts through RNA to promote HIV-1 Rev-RRE assembly. Nucleic Acids Res 45:4632-4641
Monroe, Nicole; Han, Han; Shen, Peter S et al. (2017) Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase. Elife 6:
Gu, Mingyu; LaJoie, Dollie; Chen, Opal S et al. (2017) LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proc Natl Acad Sci U S A 114:E2166-E2175
Freund, Natalia T; Wang, Haoqing; Scharf, Louise et al. (2017) Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Sci Transl Med 9:
Pak, Alexander J; Grime, John M A; Sengupta, Prabuddha et al. (2017) Immature HIV-1 lattice assembly dynamics are regulated by scaffolding from nucleic acid and the plasma membrane. Proc Natl Acad Sci U S A 114:E10056-E10065

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