Computation Core (Voth. Director) Overview Our Computation Core provides access to leading edge theory and simulation capability in atomistic molecular dynamics, coarse-graining, and multiscale modeling. While the proposed initial focus of this facility will be on HIV capsid assembly and stability, the Computation Core facility expertise will be available to all Center participants.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM082545-06
Application #
8513530
Study Section
Special Emphasis Panel (ZRG1-AARR-K (50))
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-07-31
Support Year
6
Fiscal Year
2012
Total Cost
$102,423
Indirect Cost
$12,363
Name
University of Utah
Department
Type
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
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Hammond, John A; Zhou, Li; Lamichhane, Rajan et al. (2017) A Survey of DDX21 Activity During Rev/RRE Complex Formation. J Mol Biol :
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Kieffer, Collin; Ladinsky, Mark S; Ninh, Allen et al. (2017) Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography. Elife 6:
Mamede, João I; Cianci, Gianguido C; Anderson, Meegan R et al. (2017) Early cytoplasmic uncoating is associated with infectivity of HIV-1. Proc Natl Acad Sci U S A 114:E7169-E7178
Lamichhane, Rajan; Hammond, John A; Pauszek 3rd, Raymond F et al. (2017) A DEAD-box protein acts through RNA to promote HIV-1 Rev-RRE assembly. Nucleic Acids Res 45:4632-4641
Monroe, Nicole; Han, Han; Shen, Peter S et al. (2017) Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase. Elife 6:
Gu, Mingyu; LaJoie, Dollie; Chen, Opal S et al. (2017) LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proc Natl Acad Sci U S A 114:E2166-E2175
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Pak, Alexander J; Grime, John M A; Sengupta, Prabuddha et al. (2017) Immature HIV-1 lattice assembly dynamics are regulated by scaffolding from nucleic acid and the plasma membrane. Proc Natl Acad Sci U S A 114:E10056-E10065

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