The goal of the Virus imaging core of the Utah Center for HIV Structural Biology is to develop techniques relating to correlative cryotomography and high speed single particle imaging and use these techniques to study the composition and kinetics of cytoplasmic HIV complexes.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM082545-07
Application #
8538438
Study Section
Special Emphasis Panel (ZRG1-AARR-K)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
7
Fiscal Year
2013
Total Cost
$274,330
Indirect Cost
Name
University of Utah
Department
Type
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Wang, Haoqing; Cohen, Alexander A; Galimidi, Rachel P et al. (2016) Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop. Proc Natl Acad Sci U S A 113:E7151-E7158
Monroe, Nicole; Hill, Christopher P (2016) Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines. J Mol Biol 428:1897-911
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Coey, Aaron; Larsen, Kevin; Puglisi, Joseph D et al. (2016) Heterogeneous structures formed by conserved RNA sequences within the HIV reverse transcription initiation site. RNA 22:1689-1698

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