Administrative Core Unit A fulfills three important roles forthe Center. First, the Administrative Core is responsible for the ascertainment and retention of participants for all components ofthe study. During the first day of testing. Administrative Core staff collect saliva samples from the twins, their biological siblings, and their biological parents, and mail the samples to Dr. Shelley Smith's laboratory at the University of Nebraska Medical Center so that DNA samples can be extracted, processed, and analyzed by Project IV staff. The second major responsibility of Administrative Core A is to ensure that all study data are efficiently collected, verified, and consolidated across the six research projects, and to coordinate the synthesis and distribution of an updated summary data file with data from all Research Projects every three months. Finally, in collaboration with staff on Service Core B, Service Core A staff coordinate cross-project data sharing and implement and monitor the Center-wide protocol for data sharing with external collaborators and other qualifled investigators in the field.

Public Health Relevance

Reading and writing are critically important skills for academic and professional development. Learning disabilities in these skills are important public health problems in need of better understanding of their classification and their genetic and environmental etiologies. The proposed behavior- and molecular-genetic studies on reading, writing, ADHD and related skills assessed in subjects ascertained through the Administrative Core A unit will contribute to these goals.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD027802-22
Application #
8391184
Study Section
Special Emphasis Panel (ZHD1-DSR-H)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
22
Fiscal Year
2013
Total Cost
$223,339
Indirect Cost
$75,512
Name
University of Colorado at Boulder
Department
Type
DUNS #
007431505
City
Boulder
State
CO
Country
United States
Zip Code
80309
McGrath, Lauren M (2018) Two GWASs Are Better Than One: Enhancing Genetic Discovery for Developmental Phenotypes. J Am Acad Child Adolesc Psychiatry 57:77-79
Leopold, Daniel R; Christopher, Micaela E; Olson, Richard K et al. (2018) Invariance of ADHD Symptoms Across Sex and Age: a Latent Analysis of ADHD and Impairment Ratings from Early Childhood into Adolescence. J Abnorm Child Psychol :
Aboud, Katherine S; Barquero, Laura A; Cutting, Laurie E (2018) Prefrontal mediation of the reading network predicts intervention response in dyslexia. Cortex 101:96-106
Ricker, Ashley A; Corley, Robin; DeFries, John C et al. (2018) Examining the influence of perceived stress on developmental change in memory and perceptual speed for adopted and nonadopted individuals. Dev Psychol 54:138-150
DeMille, Mellissa M C; Tang, Kevin; Mehta, Chintan M et al. (2018) Worldwide distribution of the DCDC2 READ1 regulatory element and its relationship with phoneme variation across languages. Proc Natl Acad Sci U S A 115:4951-4956
Wilkey, Eric D; Cutting, Laurie E; Price, Gavin R (2018) Neuroanatomical correlates of performance in a state-wide test of math achievement. Dev Sci 21:
Devanna, P; Chen, X S; Ho, J et al. (2018) Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders. Mol Psychiatry 23:1375-1384
Frijters, Jan C; Tsujimoto, Kimberley C; Boada, Richard et al. (2018) Reading-Related Causal Attributions for Success and Failure: Dynamic Links With Reading Skill. Read Res Q 53:127-148
Peterson, Robin L; Arnett, Anne B; Pennington, Bruce F et al. (2018) Literacy acquisition influences children's rapid automatized naming. Dev Sci 21:e12589
Becker, Stephen P; Willcutt, Erik G (2018) Advancing the study of sluggish cognitive tempo via DSM, RDoC, and hierarchical models of psychopathology. Eur Child Adolesc Psychiatry :

Showing the most recent 10 out of 201 publications