Core A: Sex Differences Administrative Support Core will be responsible for the following five services to coordinate the three projects in this SCOR.
Aim 1 : Administration: Core A will provide administrative support to Projects 1,11, and 111 for recruitment. subject scheduling, forms generation, IRB issues, organization, and confidential filing. Centralized support will decrease cost and increase effectiveness.
Aim 2 : Human Subjects: Core A will assure ongoing safety of human subjects through active involvement with our IRB committee. This involvement will assure compliance with institutional and national regulations, track and assess subject safety by monitoring adverse events, and provide information to outside subject safety committee (DSMB) as necessary. This core will prepare regular reports from centralized logs from all Projects concerning adverse events to increase detection of infrequent events that require special attention.
Aim 3 : Fostering Sex and Gender Research: Core A will seek to stimulate further research with the following activities: a) convene an annual SCOR sponsored Pelvic Floor Research Day to foster interdisciplinary discussion across campus along with translational partners and mentees, and b) support, maintain, and expand the SCOR Pelvic Floor Disorders Data Bank of over 1,200 research subjects, totaling over 20,000 images from prior and ongoing projects.
Aim 4 : Budget: Core A will manage the fiscal responsibility of Project I, II, and III along with expenses of Cores A, B, and C. This will include assurance of appropriate distribution of funds to support all three projects throughout the entire length of the funding period.
Aim 5 : Presentation and Manuscript Production: Core A will be responsible for the administrative aspects of the dissemination of data and findings to research and clinical practitioners. Manuscripts and presentations will be submitted and tracked through Core A, allowing immediate translation of important sex-differences research to the community of researchers and physicians who can implement changes and improve prevention and treatment.

Public Health Relevance

The strong central organizing activities of this administrative core will facilitate new discoveries that impact interdisciplinary sex-differences research. By promoting and supporting the broadly interdisciplinary U-M SCOR research team, Core A frees individual investigators from some management effort so they may concentrate on important insights needed to improve prevention and treatment for 3 million women giving birth and 300,000 women suffering from pelvic floor disorders.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-EMNR-Q)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Michigan Ann Arbor
Ann Arbor
United States
Zip Code
DeLancey, John O L (2017) ""Mommy, how will the baby get out of your tummy? Will it hurt you?"" Am J Obstet Gynecol 217:110-111
Harris, John A; Sammarco, Anne G; Swenson, Carolyn W et al. (2017) Are perioperative bundles associated with reduced postoperative morbidity in women undergoing benign hysterectomy? Retrospective cohort analysis of 16,286 cases in Michigan. Am J Obstet Gynecol 216:502.e1-502.e11
Sammarco, Anne G; Nandikanti, Lahari; Kobernik, Emily K et al. (2017) Interactions among pelvic organ protrusion, levator ani descent, and hiatal enlargement in women with and without prolapse. Am J Obstet Gynecol 217:614.e1-614.e7
Arenholt, Louise T S; Pedersen, Bodil Ginnerup; Glavind, Karin et al. (2017) Paravaginal defect: anatomy, clinical findings, and imaging. Int Urogynecol J 28:661-673
Reiner, Caecilia S; Williamson, Tom; Winklehner, Thomas et al. (2017) The 3D Pelvic Inclination Correction System (PICS): A universally applicable coordinate system for isovolumetric imaging measurements, tested in women with pelvic organ prolapse (POP). Comput Med Imaging Graph 59:28-37
Swenson, Carolyn W; Smith, Tovia M; Luo, Jiajia et al. (2017) Intraoperative cervix location and apical support stiffness in women with and without pelvic organ prolapse. Am J Obstet Gynecol 216:155.e1-155.e8
Fairchild, Pamela S; Kamdar, Neil S; Rosen, Emily R et al. (2017) Ligament shortening compared to vaginal colpopexy at the time of hysterectomy for pelvic organ prolapse. Int Urogynecol J 28:899-905
Zielinski, Ruth; Kane Low, Lisa; Smith, Abigail R et al. (2017) Body after baby: a pilot survey of genital body image and sexual esteem following vaginal birth. Int J Womens Health 9:189-198
DeLancey, John O L (2016) What's new in the functional anatomy of pelvic organ prolapse? Curr Opin Obstet Gynecol 28:420-9
Berger, Mitchell B; Khandwala, Nikhila; Fenner, Dee E et al. (2016) Colovaginal Fistulas: Presentation, Evaluation, and Management. Female Pelvic Med Reconstr Surg 22:355-8

Showing the most recent 10 out of 118 publications