Reading problems have negative consequences such as school failure and are associated with behavior problems that can adversely impact children's health and wellbeing. In Project IV, we will use an ethnically/racially/economically diverse sample of 866 identical and 1,725 fraternal twin pairs in grades K-6 to accomplish three specific aims that will significantly advance our understanding of reading problem phenotypes, the environmental context in which genetic risk for reading problems may be expressed, and genetic and environmental factors underlying status and stability of comorbid reading and behavior problems.
For aim 1, reading measures from Florida's Progress Monitoring and Reporting Network (PMRN) will be used to create classifications of reading problems in order to identify those that have substantial genetic influence. Behavioral, cognitive, and school/home environment data collected in year 1 ofthe project on a subsample of 350 identical and 350 same-sex fraternal twins will be used to created composites of salient environmental factors (e.g., home literacy, school resource level, classroom effectiveness) and behavior problems related to executive cognitive dysfunction (e.g., attention, impulsivity, etc.).
For aim 2, gene-environment interplay processes underlying reading problems will be identified by testing for moderating effects of salient environmental factors on genetic and environmental variance associated with reading measures from the PMRN (e.g., word reading fluency, comprehension) using biometrical models.
For aim 3, the subsample of 700 twin pairs will be re-assessed on behavior and environment measures in years 3 and 5 ofthe project and those data will be combined with PMRN reading data on the twins to estimate genetic and environmental contributions to status and stability ofthe comorbidity between reading problems and behavior problems using bivariate biometrical models.

Public Health Relevance

Reading problems are associated with school failure and behavior problems that significantly impact children's health. The proposed project will significantly advance understanding of etiological factors involved in reading problems and associated behavior problems that will inform efforts at reducing these problems and improving children's health.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD052120-08
Application #
8601725
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2014-01-01
Budget End
2014-12-31
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Florida State University
Department
Type
DUNS #
City
Tallahassee
State
FL
Country
United States
Zip Code
32306
Erbeli, Florina; Hart, Sara A; Kim, Young-Suk Grace et al. (2017) The Effects of Genetic and Environmental Factors on Writing Development. Learn Individ Differ 59:11-21
Hoff, Erika; Quinn, Jamie M; Giguere, David (2017) What explains the correlation between growth in vocabulary and grammar? New evidence from latent change score analyses of simultaneous bilingual development. Dev Sci :
Jasi?ska, Kaja K; Molfese, Peter J; Kornilov, Sergey A et al. (2017) The BDNF Val66Met polymorphism is associated with structural neuroanatomical differences in young children. Behav Brain Res 328:48-56
Kim, Grace Young-Suk; Schatschneider, Christopher; Wanzek, Jeanne et al. (2017) Writing Evaluation: Rater and Task Effects on the Reliability of Writing Scores for Children in Grades 3 and 4. Read Writ 30:1287-1310
Kim, Young-Suk Grace; Gatlin, Brandy; Al Otaiba, Stephanie et al. (2017) Theorization and an Empirical Investigation of the Component-Based and Developmental Text Writing Fluency Construct. J Learn Disabil :22219417712016
Dombek, Jennifer; Crowe, Elizabeth C; Spencer, Mercedes et al. (2017) Acquiring Science and Social Studies Knowledge in Kindergarten Through Fourth Grade: Conceptualization, Design, Implementation, and Efficacy Testing of Content-Area Literacy Instruction (CALI). J Educ Psychol 109:301-320
Little, Callie W; Haughbrook, Rasheda; Hart, Sara A (2017) Cross-Study Differences in the Etiology of Reading Comprehension: a Meta-Analytical Review of Twin Studies. Behav Genet 47:52-76
Milburn, Trelani F; Lonigan, Christopher J; Allan, Darcey M et al. (2017) Agreement Among Traditional and RTI-based Definitions of Reading-Related Learning Disability with Preschool Children. Learn Individ Differ 55:120-129
Erbeli, Florina; Hart, Sara A; Taylor, Jeanette (2017) Longitudinal Associations Among Reading-Related Skills and Reading Comprehension: A Twin Study. Child Dev :
Spiegel, Jamie A; Lonigan, Christopher J; Phillips, Beth M (2017) Factor structure and utility of the Behavior Rating Inventory of Executive Function-Preschool Version. Psychol Assess 29:172-185

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