Abstract

Statistical consultation will be provided in a substantial manner to two of the projects (White, Project 1 and Weiss, Project 5) and will always be available to the remaining three projects. Dr. Hurwitz has met with each investigator in the SCOR during the evaluation of the proposal and has addressed all necessary issues (sample size, study design, appropriate statistical testings, etc.). She will continue throughout the proposal, to [provide such statistical assistance.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL060292-03
Application #
6347607
Study Section
Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2000
Total Cost
$191,940
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Zielinski, Mark R; Gerashchenko, Dmitry; Karpova, Svetlana A et al. (2017) The NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep deprivation and lipopolysaccharide. Brain Behav Immun 62:137-150
Cori, Jennifer M; Thornton, Therese; O'Donoghue, Fergal J et al. (2017) Arousal-Induced Hypocapnia Does Not Reduce Genioglossus Activity in Obstructive Sleep Apnea. Sleep 40:
Chen, Michael C; Ferrari, Loris; Sacchet, Matthew D et al. (2015) Identification of a direct GABAergic pallidocortical pathway in rodents. Eur J Neurosci 41:748-59
Kim, Youngsoo; Elmenhorst, David; Weisshaupt, Angela et al. (2015) Chronic sleep restriction induces long-lasting changes in adenosine and noradrenaline receptor density in the rat brain. J Sleep Res 24:549-558
Zielinski, Mark R; Kim, Youngsoo; Karpova, Svetlana A et al. (2014) Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression. Neurosci Lett 580:27-31
Lim, Andrew S P; Ellison, Brian A; Wang, Joshua L et al. (2014) Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease. Brain 137:2847-61
Zielinski, M R; Kim, Y; Karpova, S A et al. (2013) Sleep active cortical neurons expressing neuronal nitric oxide synthase are active after both acute sleep deprivation and chronic sleep restriction. Neuroscience 247:35-42
McCoy, John G; Christie, Michael A; Kim, Youngsoo et al. (2013) Chronic sleep restriction impairs spatial memory in rats. Neuroreport 24:91-5
Kim, Youngsoo; Chen, Lichao; McCarley, Robert W et al. (2013) Sleep allostasis in chronic sleep restriction: the role of the norepinephrine system. Brain Res 1531:9-16
McKenna, James Timothy; Christie, Michael A; Jeffrey, Brianne A et al. (2012) Chronic ramelteon treatment in a mouse model of Alzheimer's disease. Arch Ital Biol 150:5-14

Showing the most recent 10 out of 148 publications