The Tobacco Product Evaluation and Expose Core (Core B) will provide members of AHA Tobacco Regulation and Addiction Center (A-TRAC) the research capabilities to identify and evaluate tobacco product composition and constituents;to perform realistic tobacco product exposures in animal models such that delivery of tobacco products that replicates real world human exposures;to measure biomarkers of tobacco exposure;and to develop analytical techniques and approaches that improve our understanding of the complex relationship between markers of tobacco exposure and biomarkers of cardiovascular injury (see Core C). The Core will serve both the needs of Center projects and be an active research Core in its own right as it develops new and improved techniques that enhance the breadth and sensitivity of detection of tobacco product constituents and promotes better understanding of new and emerging tobacco products.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-BDCN-Q (40))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
American Heart Association
United States
Zip Code
Fox, Caroline S; Hwang, Shih-Jen; Nieto, Kenneth et al. (2016) Digital Connectedness in the Framingham Heart Study. J Am Heart Assoc 5:e003193
Bhatnagar, Aruni (2016) Cardiovascular Perspective of the Promises and Perils of E-Cigarettes. Circ Res 118:1872-5
Wu, Yangfeng; Benjamin, Emelia J; MacMahon, Stephen (2016) Prevention and Control of Cardiovascular Disease in the Rapidly Changing Economy of China. Circulation 133:2545-60
Campion, MaryAnn W; Bhasin, Robina M; Beaudette, Donald J et al. (2016) Mid-career faculty development in academic medicine: How does it impact faculty and institutional vitality? J Fac Dev 30:49-64
Conklin, Daniel J; Haberzettl, Petra; Jagatheesan, Ganapathy et al. (2016) Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein. Toxicol Appl Pharmacol :
Vasan, Ramachandran S; Benjamin, Emelia J (2016) The Future of Cardiovascular Epidemiology. Circulation 133:2626-33
Conklin, Daniel J (2016) Acute cardiopulmonary toxicity of inhaled aldehydes: role of TRPA1. Ann N Y Acad Sci 1374:59-67
Rahman, Faisal; Yin, Xiaoyan; Larson, Martin G et al. (2016) Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study. Hypertension 68:597-605
Lee, Jane J; Yin, Xiaoyan; Hoffmann, Udo et al. (2016) Relation of Pericardial Fat, Intrathoracic Fat, and Abdominal Visceral Fat With Incident Atrial Fibrillation (from the Framingham Heart Study). Am J Cardiol 118:1486-1492
Fetterman, Jessica L; Holbrook, Monica; Westbrook, David G et al. (2016) Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease. Cardiovasc Diabetol 15:53

Showing the most recent 10 out of 16 publications