Abstract

DEVELOPMENTAL AND PILOT RESEARCH COMPONENT: As TCORS research progresses and a new base of knowledge develops, further research opportunities will arise. Such opportunities will include new research ideas, validation studies, and interventional projects. To foster a continuation of scientific inquiry related to both TCORS goals and FDA needs, A-TRAC proposes to develop a Developmental and Pilot Research Component to promote the exploration of new ideas by developing and implementing pilot research projects. Similar to the Center's overall structure, these pilot projects will operate across major research proposals and will be supported by A-TRAC at different academic institutions, both within and external to the TCORS network. In collaboration with the Administrative Core, the Developmental and Pilot Research Component will utilize the already existing AHA plan of solicitation and peer-review to select individual projects for funding. These projects will be expected to be both scientifically sound and rigorous, and must also address the research priorities of the FDA. The AHA has strong competencies in research review and administration that will allow for an effective partnership with the FDA .

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL120163-03
Application #
8906928
Study Section
Special Emphasis Panel (ZRG1-BDCN-A)
Project Start
Project End
2016-06-30
Budget Start
2015-09-01
Budget End
2016-08-31
Support Year
3
Fiscal Year
2015
Total Cost
$406,277
Indirect Cost
$5,231

  Institution

Name
American Heart Association
Department
Type
DUNS #
073284507
City
Dallas
State
TX
Country
United States
Zip Code
75231

  Publications

Lee, Alexander S; Hart, Joy L; Walker, Kandi L et al. (2018) Dual Users and Electronic Cigarette Only Users: Consumption and Characteristics. Int J Healthc Med Sci 4:111-116
Staerk, Laila; Wang, Biqi; Preis, Sarah R et al. (2018) Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study. BMJ 361:k1453
Bahelah, Raed; Ward, Kenneth D; Ben Taleb, Ziyad et al. (2018) Determinants of progression of nicotine dependence symptoms in adolescent waterpipe smokers. Tob Control :
Weaver, Scott R; Kim, Hyoshin; Glasser, Allison M et al. (2018) Establishing consensus on survey measures for electronic nicotine and non-nicotine delivery system use: Current challenges and considerations for researchers. Addict Behav 79:203-212
Mwasongwe, Stanford; Min, Yuan-I; Booth 3rd, John N et al. (2018) Masked hypertension and kidney function decline: the Jackson Heart Study. J Hypertens 36:1524-1532
Keith, Rachel J; Fetterman, Jessica L; Riggs, Daniel W et al. (2018) Protocol to assess the impact of tobacco-induced volatile organic compounds on cardiovascular risk in a cross- sectional cohort: Cardiovascular Injury due to Tobacco Use study. BMJ Open 8:e019850
Mwasongwe, Stanford E; Young, Bessie; Bidulescu, Aurelian et al. (2018) Relation of multi-marker panel to incident chronic kidney disease and rapid kidney function decline in African Americans: the Jackson Heart Study. BMC Nephrol 19:239
Gibson, Laura A; Creamer, MeLisa R; Breland, Alison B et al. (2018) Measuring perceptions related to e-cigarettes: Important principles and next steps to enhance study validity. Addict Behav 79:219-225
Riggs, Daniel W; Yeager, Ray A; Bhatnagar, Aruni (2018) Defining the Human Envirome: An Omics Approach for Assessing the Environmental Risk of Cardiovascular Disease. Circ Res 122:1259-1275
Fetterman, Jessica L; Weisbrod, Robert M; Feng, Bihua et al. (2018) Flavorings in Tobacco Products Induce Endothelial Cell Dysfunction. Arterioscler Thromb Vasc Biol 38:1607-1615

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