CORE 6: CHRONIC SCHIZOPHRENIA ASSESSMENT AND RECRUITMENT CORE The primary function ofthe Chronic Schizophrenia Recruitment and Assessment Core will be to recruit andclinically assess chronic schizophrenia patients and demographically comparable normal subjects for participation in projects ofthe Center for Neurocognition and Emotion in Schizophrenia. By centralizing the recruitment of chronic patients in a single Core, the aim is to increase the efficiency ofthe process and eliminate the need for individual projects to set up redundant recruitment mechanisms. To maximize the demographic similarity ofthe chronic sample to the other samples in the Center, chronic schizophrenia subjects will be recruited from former participants in prior longitudinal studies of first-episode patients conducted at the Aftercare Research Program who have had their onset of illness at least five years prior to enrollment in the Center research. This Core will screen, recruit, and conduct diagnostic interviews with the patient subjects and the normal comparison subjects. Staff from this Core will also complete ratings of symptom severity, functional capacity, functional outcome, and neurocognition for all subjects participating in this Core. In addition, this Core will facilitate and coordinate the involvement of these patient and normal subjects in Center projects, including the coordination of laboratory access at UCLA. Unlike the Prodromal Research Program and the Aftercare Research Program, no treatment is provided for these patients as partof their Center participation.
The specific aims ofthis Core are to: 1) recruit and evaluate patients with chronic schizophrenia from former participants ofthe UCLA Aftercare Program, 2) To conduct diagnostic, symptom, functional outcome, and neurocognitive assessments of Chronic patients who will be participating in Center project protocols, 3) To recruit, screen, and complete diagnostic, symptom, functional outcome, and neurocognitive assessments with demographically comparable normal comparison subjects, 4) To facilitate and coordinate the participation of chronic schizophrenia patients and demographically comparable normal subjects in the Center projects.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZMH1-ERB-N)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Los Angeles
United States
Zip Code
Addington, Jean; Piskulic, Danijela; Liu, Lu et al. (2017) Comorbid diagnoses for youth at clinical high risk of psychosis. Schizophr Res 190:90-95
Nuechterlein, Keith H (2017) The Pioneering Contributions of Irving Gottesman: An Appreciation. Clin Psychol Sci 5:424-426
Hamilton, Holly K; Williams, Terrance J; Ventura, Joseph et al. (2017) Clinical and Cognitive Significance of Auditory Sensory Processing Deficits in Schizophrenia. Am J Psychiatry :appiajp201716111203
McLaughlin, Danielle; CarriĆ³n, Ricardo E; Auther, Andrea M et al. (2016) Functional Capacity Assessed by the Map Task in Individuals at Clinical High-Risk for Psychosis. Schizophr Bull 42:1234-42
Deighton, Stephanie; Buchy, Lisa; Cadenhead, Kristin S et al. (2016) Traumatic brain injury in individuals at clinical high risk for psychosis. Schizophr Res 174:77-81
McCleery, Amanda; Lee, Junghee; Fiske, Alan P et al. (2016) Longitudinal stability of social cognition in schizophrenia: A 5-year follow-up of social perception and emotion processing. Schizophr Res 176:467-472
Moskow, Danielle M; Addington, Jean; Bearden, Carrie E et al. (2016) The relations of age and pubertal development with cortisol and daily stress in youth at clinical risk for psychosis. Schizophr Res 172:29-34
Buchy, Lisa; Mathalon, Daniel H; Cannon, Tyrone D et al. (2016) Relation between cannabis use and subcortical volumes in people at clinical high risk of psychosis. Psychiatry Res 254:3-9
Lake, Jessica I; LaBar, Kevin S; Meck, Warren H (2016) Emotional modulation of interval timing and time perception. Neurosci Biobehav Rev 64:403-20
Seidman, Larry J; Shapiro, Daniel I; Stone, William S et al. (2016) Association of Neurocognition With Transition to Psychosis: Baseline Functioning in the Second Phase of the North American Prodrome Longitudinal Study. JAMA Psychiatry 73:1239-1248

Showing the most recent 10 out of 129 publications