CORE 5: AFTERCARE RESEARCH PROGRAM The Aftercare Research Program is an outpatient research clinic at the UCLA Semel Institute for Neuroscience &Human Behavior that will provide the clinical site for the recruitment, pharmacological and psychosocial interventions, and assessments of symptoms and functional outcome for first-episode patients who are participating in research projects in this Center. The primary mission of the Aftercare Program is to provide a structured and high quality clinical care setting within which this Center research can take place. The Aftercare Research Program will provide a centralized and standardized process for screening and diagnosing first-episode schizophrenia patient participants, providing their clinical services, and completing high-quality longitudinal assessments of symptoms, work functioning, and social functioning. As detailed in the budget justification section for this Core, this centralization will result in great savings to the multiple individual projects that involve Aftercare Program patients, compared to costs if these research projects were carried out independently. Furthermore, by utilizing a shared group of first-episode patients, opportunities for integrative data analyses across projects will become available. A second function is to optimize the level of patient participation in Center-related research projects. A third function is to provide a sample of normal subjects, demogi'aphically comparable to the first-episode patients, for potential participation in Center-affiliated projects. A fourth function ofthe Aftercare Research Program is to provide a convenient group of patient volunteers for the piloting of new measures being developed by individual projects and by the Functional Outcome and Symptom Assessment Core. A fifth function is to offer a research training site for predoctoral and post-doctoral research fellows to encourage development of new translational researchers. Three psychiatrists, and one doctoral level and two masters level therapists, will provide the clinical interventions and research assessments in space allocated to the Program in the UCLA Medical Plaza.

Agency
National Institute of Health (NIH)
Type
Specialized Center (P50)
Project #
5P50MH066286-10
Application #
8705593
Study Section
Special Emphasis Panel (ZMH1)
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Tsai, Katherine H; López, Steve; Marvin, Sarah et al. (2015) Perceptions of family criticism and warmth and their link to symptom expression in racially/ethnically diverse adolescents and young adults at clinical high risk for psychosis. Early Interv Psychiatry 9:476-86
Nuechterlein, Keith H; Ventura, Joseph; Subotnik, Kenneth L et al. (2014) Developing a Cognitive Training Strategy for First-Episode Schizophrenia: Integrating Bottom-Up and Top-Down Approaches. Am J Psychiatr Rehabil 17:225-253
McCleery, A; Ventura, J; Kern, R S et al. (2014) Cognitive functioning in first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) Profile of Impairment. Schizophr Res 157:33-9
Nuechterlein, Keith H; Ventura, Joseph; Subotnik, Kenneth L et al. (2014) The early longitudinal course of cognitive deficits in schizophrenia. J Clin Psychiatry 75 Suppl 2:25-9
Hamilton, Holly K; Sun, Jane C; Green, Michael F et al. (2014) Social cognition and functional outcome in schizophrenia: The moderating role of cardiac vagal tone. J Abnorm Psychol 123:764-70
Ventura, Joseph; Subotnik, Kenneth L; Ered, Arielle et al. (2014) The relationship of attitudinal beliefs to negative symptoms, neurocognition, and daily functioning in recent-onset schizophrenia. Schizophr Bull 40:1308-18
Subotnik, Kenneth L; Ventura, Joseph; Gretchen-Doorly, Denise et al. (2014) The impact of second-generation antipsychotic adherence on positive and negative symptoms in recent-onset schizophrenia. Schizophr Res 159:95-100
Karlsgodt, Katherine H; van Erp, Theo G M; Bearden, Carrie E et al. (2014) Altered relationships between age and functional brain activation in adolescents at clinical high risk for psychosis. Psychiatry Res 221:21-9
Golembo-Smith, Shana; Bachman, Peter; Senturk, Damla et al. (2014) Youth-caregiver agreement on clinical high-risk symptoms of psychosis. J Abnorm Child Psychol 42:649-58
Ventura, Joseph; Reise, Steven P; Keefe, Richard S E et al. (2013) The Cognitive Assessment Interview (CAI): reliability and validity of a brief interview-based measure of cognition. Schizophr Bull 39:583-91

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