Core B is the Biostafistics and Data Management Core which is responsible for developing and maintaining a relational database of demographic, clinical, genetic, biomarker, and other data gathered by SCOR projects described in the application to examine the impact of early life adversity on the development of stress dysregulation. This core provides database, compufing, and biostatistical direction and analysis support to the research pursued in Projects l-lll. Lastly, Core B will employ and extend existing methodologies for the analysis of the SCOR project data.
Early life adversity is one of the greatest predictors of affective disorder onset in women. Core B will provide database, compufing, and biostatistical direcfion and analysis support to the research pursued in Projects I- III.
|Goel, Namni; Bale, Tracy L; Epperson, C Neill et al. (2014) Effects of sex and gender on adaptation to space: behavioral health. J Womens Health (Larchmt) 23:975-86|
|Howerton, Alexis R; Roland, Alison V; Bale, Tracy L (2014) Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation. J Neurosci 34:7113-23|
|Howerton, Christopher L; Bale, Tracy L (2014) Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction. Proc Natl Acad Sci U S A 111:9639-44|
|Altemus, Margaret; Sarvaiya, Nilofar; Neill Epperson, C (2014) Sex differences in anxiety and depression clinical perspectives. Front Neuroendocrinol 35:320-30|
|Morrison, K E; Rodgers, A B; Morgan, C P et al. (2014) Epigenetic mechanisms in pubertal brain maturation. Neuroscience 264:17-24|
|Kim, Deborah R; Hantsoo, Liisa; Thase, Michael E et al. (2014) Computer-assisted cognitive behavioral therapy for pregnant women with major depressive disorder. J Womens Health (Larchmt) 23:842-8|
|Hantsoo, Liisa; Ward-O'Brien, Deborah; Czarkowski, Kathryn A et al. (2014) A randomized, placebo-controlled, double-blind trial of sertraline for postpartum depression. Psychopharmacology (Berl) 231:939-48|
|Boersma, G J; Bale, T L; Casanello, P et al. (2014) Long-term impact of early life events on physiology and behaviour. J Neuroendocrinol 26:587-602|
|Epperson, C Neill; Kim, Deborah R; Bale, Tracy L (2014) Estradiol modulation of monoamine metabolism: one possible mechanism underlying sex differences in risk for depression and dementia. JAMA Psychiatry 71:869-70|
|Hantsoo, Liisa; Czarkowski, Kathryn A; Child, Josiah et al. (2014) Selective serotonin reuptake inhibitors and endothelial function in women. J Womens Health (Larchmt) 23:613-8|
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