Core B is the Biostafistics and Data Management Core which is responsible for developing and maintaining a relational database of demographic, clinical, genetic, biomarker, and other data gathered by SCOR projects described in the application to examine the impact of early life adversity on the development of stress dysregulation. This core provides database, compufing, and biostatistical direction and analysis support to the research pursued in Projects l-lll. Lastly, Core B will employ and extend existing methodologies for the analysis of the SCOR project data.

Public Health Relevance

Early life adversity is one of the greatest predictors of affective disorder onset in women. Core B will provide database, compufing, and biostatistical direcfion and analysis support to the research pursued in Projects I- III.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH099910-02
Application #
8522242
Study Section
Special Emphasis Panel (ZRG1-EMNR-Q)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
2
Fiscal Year
2013
Total Cost
$68,689
Indirect Cost
$25,758
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Boersma, G J; Bale, T L; Casanello, P et al. (2014) Long-term impact of early life events on physiology and behaviour. J Neuroendocrinol 26:587-602
Epperson, C Neill; Kim, Deborah R; Bale, Tracy L (2014) Estradiol modulation of monoamine metabolism: one possible mechanism underlying sex differences in risk for depression and dementia. JAMA Psychiatry 71:869-70
Hantsoo, Liisa; Czarkowski, Kathryn A; Child, Josiah et al. (2014) Selective serotonin reuptake inhibitors and endothelial function in women. J Womens Health (Larchmt) 23:613-8

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