An Administrative Core will provide support for all Conte Center activities. The Administrative Core will be directed by Richard Huganir and the daily activities will be performed by two administrators. The Administrators will arrange consultant activities, manage budgets, order supplies, monitor inventory, and provide secretarial support for the PI. In addition, the Core Administrator will also manage the Conte Center web site. The Administrative Core will be located in the Administrative Office Suite for the Department of Neuroscience, Room 1001 ofthe Woods Basic Science Building. This room is located near the office ofthe PI and within one or two floors of each of the Conte Center Labs.
This Administartive Core will provide support for the Conte Center consisting of seven laboratories that are studying the molecular and cellular mechanisms underiying plasticity at the excitatory synapse. Recent studies have demonstrated that many neurological and psychiatric diseases result from defects in excitatory synaptic transmission and plasticity. This research may therefore reveal novel targets for the development of therapeutic treatments for several brain disorders including schizophrenia autism and depression.
| Piard, Juliette; Hu, Jia-Hua; Campeau, Philippe M et al. (2018) FRMPD4 mutations cause X-linked intellectual disability and disrupt dendritic spine morphogenesis. Hum Mol Genet 27:589-600 |
| Diering, Graham H; Huganir, Richard L (2018) The AMPA Receptor Code of Synaptic Plasticity. Neuron 100:314-329 |
| Heo, Seok; Diering, Graham H; Na, Chan Hyun et al. (2018) Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover. Proc Natl Acad Sci U S A 115:E3827-E3836 |
| Xiao, Mei-Fang; Xu, Desheng; Craig, Michael T et al. (2017) NPTX2 and cognitive dysfunction in Alzheimer's Disease. Elife 6: |
| Ryu, Changhyeon; Jang, Dong Cheol; Jung, Dayoon et al. (2017) STIM1 Regulates Somatic Ca2+ Signals and Intrinsic Firing Properties of Cerebellar Purkinje Neurons. J Neurosci 37:8876-8894 |
| Akassoglou, Katerina; Merlini, Mario; Rafalski, Victoria A et al. (2017) In Vivo Imaging of CNS Injury and Disease. J Neurosci 37:10808-10816 |
| Li, Ang; Liang, Wenxuan; Guan, Honghua et al. (2017) Focus scanning with feedback-control for fiber-optic nonlinear endomicroscopy. Biomed Opt Express 8:2519-2527 |
| Wang, Qiang; Chiu, Shu-Ling; Koropouli, Eleftheria et al. (2017) Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons. Neuron 96:1084-1098.e7 |
| Roth, Richard H; Zhang, Yong; Huganir, Richard L (2017) Dynamic imaging of AMPA receptor trafficking in vitro and in vivo. Curr Opin Neurobiol 45:51-58 |
| Diering, Graham H; Nirujogi, Raja S; Roth, Richard H et al. (2017) Homer1a drives homeostatic scaling-down of excitatory synapses during sleep. Science 355:511-515 |
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