The primary focus of the proposed research will be to study the biological basis of implicit memory function. Specifically, patients with unilateral neocortical lesions will be assessed on a variety of implicit memory tests. Subjects will include patients with dorsolateral prefrontal lesions, patients with temporal-parietal lesions, and patients with occipital lesions. Various tests of implicit memory (e.g., tests of perceptual, lexical, and semantic priming) and various stimulus material (e.g., verbal, nonverbal) will be used to determine patterns of impairment on these tests in patients with neocortical lesions. It is predicted that secondary sensory areas (e.g., prestriate occipital areas) will be critical for perceptual priming, temporal-parietal associational areas will be critical for lexical priming, and frontal areas will be critical for semantic priming.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS017778-17
Application #
6112177
Study Section
Project Start
1998-07-01
Project End
1999-06-30
Budget Start
Budget End
Support Year
17
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Shimamura, Arthur P; Marian, Diane E; Haskins, Andrew L (2013) Neural correlates of emotional regulation while viewing films. Brain Imaging Behav 7:77-84
Shimamura, Arthur P (2010) Hierarchical relational binding in the medial temporal lobe: the strong get stronger. Hippocampus 20:1206-16
Shimamura, Arthur P; Wickens, Thomas D (2009) Superadditive memory strength for item and source recognition: the role of hierarchical relational binding in the medial temporal lobe. Psychol Rev 116:1-19
Miller, Michael B; Donovan, Christa-Lynn; Van Horn, John D et al. (2009) Unique and persistent individual patterns of brain activity across different memory retrieval tasks. Neuroimage 48:625-35
Mullette-Gillman, O'Dhaniel A; Cohen, Yale E; Groh, Jennifer M (2009) Motor-related signals in the intraparietal cortex encode locations in a hybrid, rather than eye-centered reference frame. Cereb Cortex 19:1761-75
Turken, Andu; Whitfield-Gabrieli, Susan; Bammer, Roland et al. (2008) Cognitive processing speed and the structure of white matter pathways: convergent evidence from normal variation and lesion studies. Neuroimage 42:1032-44
Tillmann, Barbara; Janata, Petr; Birk, Jeffrey et al. (2008) Tonal centers and expectancy: facilitation or inhibition of chords at the top of the harmonic hierarchy? J Exp Psychol Hum Percept Perform 34:1031-43
Putnam, Mary Colvin; Wig, Gagan S; Grafton, Scott T et al. (2008) Structural organization of the corpus callosum predicts the extent and impact of cortical activity in the nondominant hemisphere. J Neurosci 28:2912-8
Dowman, R; Darcey, T; Barkan, H et al. (2007) Human intracranially-recorded cortical responses evoked by painful electrical stimulation of the sural nerve. Neuroimage 34:743-63
Janata, Petr (2005) Brain networks that track musical structure. Ann N Y Acad Sci 1060:111-24

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