Narcolepsy-cataplexy is a serious and chronic sleep disorder resulting in excessive daytime sleepiness and cataplexy. It is one of the most common neurological disorders, affecting approximately 1 in 2,000 individuals in North America. This multidisciplinary project focuses on the study of human narcolepsy and seeks to identify the genetic and environmental factors involved in triggering narcolepsy. We also want to understand why the immune system destroys hypocretin neurons in narcolepsy and to prevent/cure it.

Public Health Relevance

Narcolepsy-cataplexy is a serious and chronic sleep disorder resulting in excessive daytime sleepiness and cataplexy, and this project seeks to discover the factors involved in triggering human narcolepsy.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS023724-26
Application #
8517210
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Program Officer
He, Janet
Project Start
1997-06-01
Project End
2016-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
26
Fiscal Year
2013
Total Cost
$1,191,978
Indirect Cost
$349,660
Name
Stanford University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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