The Neuroscience Core will provide general laboratory services including maintenance and repair of all Core laboratory equipment used by the Principal Investigators, as well as part-time dishwashing services. Additional services to be provided are the annual maintenance and calibration of precision balances belonging to the principal investigators on this floor, as well as common supplies used by all laboratories, such as wet and dry ice, and common laboratory gases. The core will be directed by Dr. Serge Przedborski. Dr. Vernice Jackson-Lewis will manage the day-to-day activities of the Core. This will include the identification of any problems, initiation of all necessary remedies, and the alerting of researchers and staff members on the floor of the situation. Any issues related to the Neuroscience Core will be discussed at the regular Udall Center meetings, attended by all members of the executive committee of the Udall Center at Columbia University.

Public Health Relevance

Neuroscience research requires the acquisition and maintenance of large, expensive pieces of equipment which individual labs can often not afford. By providing access to shared equipment, the Neuroscience Core is essential to our mission of deciphering the cause and mechanism of Parkinson's disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS038370-14
Application #
8382700
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
14
Fiscal Year
2012
Total Cost
$85,444
Indirect Cost
$32,350
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Wu, Di; Klaw, Michelle C; Kholodilov, Nikolai et al. (2016) Expressing Constitutively Active Rheb in Adult Dorsal Root Ganglion Neurons Enhances the Integration of Sensory Axons that Regenerate Across a Chondroitinase-Treated Dorsal Root Entry Zone Following Dorsal Root Crush. Front Mol Neurosci 9:49
Louis, Elan D; Clark, Lorraine; Ottman, Ruth (2016) Familial Aggregation and Co-Aggregation of Essential Tremor and Parkinson's Disease. Neuroepidemiology 46:31-6
Guerreiro, Rita; Escott-Price, Valentina; Darwent, Lee et al. (2016) Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiol Aging 38:214.e7-10
Pereira, Daniela B; Schmitz, Yvonne; Mészáros, József et al. (2016) Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum. Nat Neurosci 19:578-86
Tambini, Marc D; Pera, Marta; Kanter, Ellen et al. (2016) ApoE4 upregulates the activity of mitochondria-associated ER membranes. EMBO Rep 17:27-36
Clark, L N; Ye, X; Liu, X et al. (2015) Genetic analysis of ten common degenerative hereditary ataxia loci in patients with essential tremor. Parkinsonism Relat Disord 21:943-7
Saunders-Pullman, Rachel; Alcalay, Roy N; Mirelman, Anat et al. (2015) REM sleep behavior disorder, as assessed by questionnaire, in G2019S LRRK2 mutation PD and carriers. Mov Disord 30:1834-9
Aimé, Pascaline; Sun, Xiaotian; Zareen, Neela et al. (2015) Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. J Neurosci 35:10731-49
Pasini, Silvia; Corona, Carlo; Liu, Jin et al. (2015) Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory. Cell Rep 11:183-91
Cebrián, Carolina; Loike, John D; Sulzer, David (2015) Neuroinflammation in Parkinson's disease animal models: a cell stress response or a step in neurodegeneration? Curr Top Behav Neurosci 22:237-70

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