The goal of the Data Management and Biostatistics Core is to provide statistical and study design support to achieve the overall goal of PANUC;Understanding basic mechanisms that underiie cognitive impairment in PD. To achieve this goal, the Data Management and Biostatistics Core has the following four specific aims:
Aim 1. Enhance research productivity by serving a coordinating role for database development, data cleaning and organization for individual projects.
Aim 2. Facilitate conduct of PANUC projects by providing statistical and methodological support, data analysis and interpretation of results.
Aim 3. Foster collaborative research by facilitating data sharing across PANUC projects.
Aim 4. Facilitate dissemination of study results by assisting in manuscript development and preparation, and in organizing and preparing data for submission to national repositories and databases as required by NIH.
(See Instructions): It is imperative that data management is well organized and that appropriate statistical methods are applied to ensure valid and meaningful results. The Data Management and Biostatistics Core (Core D) will provide this expertise to the Pacific Northwest Udall Center (PANUC), and will play a crucial role in discovering and investigating the mechanisms that underiie cognitive impairment in PD.
|Chahine, Lama M; Stern, Matthew B; Chen-Plotkin, Alice (2014) Blood-based biomarkers for Parkinson's disease. Parkinsonism Relat Disord 20 Suppl 1:S99-103|
|Mata, Ignacio F; Leverenz, James B; Weintraub, Daniel et al. (2014) APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease. JAMA Neurol 71:1405-12|
|Shi, Min; Liu, Changqin; Cook, Travis J et al. (2014) Plasma exosomal ?-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol 128:639-50|
|Burdick, Daniel J; Cholerton, Brenna; Watson, G S et al. (2014) People with Parkinson's disease and normal MMSE score have a broad range of cognitive performance. Mov Disord 29:1258-64|
|Gallardo, Christian M; Darvas, Martin; Oviatt, Mia et al. (2014) Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice. Elife 3:e03781|
|Halliday, Glenda M; Leverenz, James B; Schneider, Jay S et al. (2014) The neurobiological basis of cognitive impairment in Parkinson's disease. Mov Disord 29:634-50|
|Darvas, Martin; Henschen, Charles W; Palmiter, Richard D (2014) Contributions of signaling by dopamine neurons in dorsal striatum to cognitive behaviors corresponding to those observed in Parkinson's disease. Neurobiol Dis 65:112-23|
|Cohen, Rajal G; Klein, Krystal A; Nomura, Mariko et al. (2014) Inhibition, executive function, and freezing of gait. J Parkinsons Dis 4:111-22|
|Nuytemans, Karen; Inchausti, Vanessa; Beecham, Gary W et al. (2014) Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease. Mov Disord 29:827-30|
|Stewart, Tessandra; Sui, Yu-Ting; Gonzalez-Cuyar, Luis F et al. (2014) Cheek cell-derived *-synuclein and DJ-1 do not differentiate Parkinson's disease from control. Neurobiol Aging 35:418-20|
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