The WaNPRC Pilot Program provides support for innovative and potentially high risk, high impact preliminary studies using nonhuman primates. The program goals include developing new nonhuman primate models for biomedical research, acquiring preliminary data for subsequent grant application, or successive human clinical studies. This program is significant in that funding for preliminary, explorative investigation is extremely difficult to secure. The Pilot Program offers PIs an opportunity to obtain limited support for preliminary studies focused on development of new models or ?proof of concept?. These studies can potentially provide significant impact through development of new NHP models or providing essential preliminary data for subsequent grant submission. In some cases, these studies can provide necessary information to inform decisions for ensuing human clinical studies. The WaNPRC Pilot program is conducted collaboratively with the Institute for Translational Health Sciences at the University of Washington.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Primate Research Center Grants (P51)
Project #
2P51OD010425-56
Application #
9207551
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2017-05-01
Budget End
2018-04-30
Support Year
56
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Washington
Department
Veterinary Sciences
Type
Primate Centers
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hogan, Michael J; Conde-Motter, Angela; Jordan, Andrea P O et al. (2018) Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization. Virology 514:106-117
Patton, Dorothy L; Sweeney, Yvonne C; Baldessari, Audrey E et al. (2018) The Chlamydia trachomatis Plasmid and CT135 Virulence Factors Are Not Essential for Genital Tract Infection or Pathology in Female Pig-Tailed Macaques. Infect Immun 86:
Hensley-McBain, Tiffany; Berard, Alicia R; Manuzak, Jennifer A et al. (2018) Intestinal damage precedes mucosal immune dysfunction in SIV infection. Mucosal Immunol 11:1429-1440
Meister, Miriam L R; Buffalo, Elizabeth A (2018) Neurons in primate entorhinal cortex represent gaze position in multiple spatial reference frames. J Neurosci :
Adams Waldorf, Kristina M; Nelson, Branden R; Stencel-Baerenwald, Jennifer E et al. (2018) Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain. Nat Med 24:368-374
Mitchell, Timothy; MacDonald, James W; Srinouanpranchanh, Sengkeo et al. (2018) Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman primates. Am J Obstet Gynecol 218:438.e1-438.e16
Choi, Hannah; Pasupathy, Anitha; Shea-Brown, Eric (2018) Predictive Coding in Area V4: Dynamic Shape Discrimination under Partial Occlusion. Neural Comput 30:1209-1257
Cole, Amy L; Cosgrove Sweeney, Yvonne; Lasseter, Amanda G et al. (2018) Evaluation of the Pig-Tailed Macaque (Macaca nemestrina) as a Model of Human Staphylococcus aureus Nasal Carriage. Infect Immun 86:
Kraft, John C; Treuting, Piper M; Ho, Rodney J Y (2018) Indocyanine green nanoparticles undergo selective lymphatic uptake, distribution and retention and enable detailed mapping of lymph vessels, nodes and abnormalities. J Drug Target 26:494-504
Gulinello, Maria; Mitchell, Heather A; Chang, Qiang et al. (2018) Rigor and reproducibility in rodent behavioral research. Neurobiol Learn Mem :

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