The California National Primate Research Center (CNPRC) Is one of eight National Primate Research Centers (NPRCs) funded by the National Institutes of Health, National Center for Research Resource. This renewal application seeksisupport for Administrative Services, Primate Services, Core Science Services, Research Units and Modernization and Improvement. To enhance the CNPRC's ability to serve as a regional, national, and international resource and provide the infrastructure support essential to conduct successful research on nonhuman primates, we are proposing the following specific aims. 1) Advance translational research through the development of nonhuman primate models; 2) Foster an environment that encourages and emphasizes the scientific expertise that is critical to carry out the mission of the NPRC Program and the CNPRC; 3) Encourage partnerships to maximize the research investment; 4) Enhance the research infrastructure; 5) Strengthen the research workforce; 6) Increase efficiencies in the use of CNPRC resources.

Public Health Relevance

The CNPRC will expand collaborations to enhance translational research through the development of new nonhuman primate models of disease by utilizing basic knowledge and technologies of Staff Scientists and scientists outside of the CNPRC.

National Institute of Health (NIH)
Office of The Director, National Institutes of Health (OD)
Primate Research Center Grants (P51)
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Special Emphasis Panel (ZRR1-CM-5 (01))
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Harding, John D
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University of California Davis
Veterinary Sciences
Schools of Veterinary Medicine
United States
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Kelly, K R; Pypendop, B H; Christe, K L (2015) Pharmacokinetics of tramadol following intravenous and oral administration in male rhesus macaques (Macaca mulatta). J Vet Pharmacol Ther 38:375-82
Wussow, Felix; Chiuppesi, Flavia; Martinez, Joy et al. (2014) Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex. PLoS Pathog 10:e1004524
Allen, Roblee P; Schelegle, Edward S; Bennett, Stephen H (2014) Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype. Am J Physiol Heart Circ Physiol 307:H405-17
Kinnally, E L (2014) Epigenetic plasticity following early stress predicts long-term health outcomes in rhesus macaques. Am J Phys Anthropol 155:192-9
Nicol, Lindsey E; O'Brien, Timothy D; Dumesic, Daniel A et al. (2014) Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. PLoS One 9:e106527
Tarantal, Alice F; Berglund, Lars (2014) Obesity and lifespan health--importance of the fetal environment. Nutrients 6:1725-36
Rainnie, Donald G; Hazra, Rimi; Dabrowska, Joanna et al. (2014) Distribution and functional expression of Kv4 family * subunits and associated KChIP * subunits in the bed nucleus of the stria terminalis. J Comp Neurol 522:609-25
Kelly, Kristi R; Pypendop, Bruno H; Christe, Kari L (2014) Pharmacokinetics of hydromorphone after intravenous and intramuscular administration in male rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 53:512-6
Kanthaswamy, Sree; Elfenbein, Hanie A; Ardeshir, Amir et al. (2014) Familial aggregation of chronic diarrhea disease (CDD) in rhesus macaques (Macaca mulatta). Am J Primatol 76:262-70
Murphy, Shannon R; Oslund, Karen L; Hyde, Dallas M et al. (2014) Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. Am J Physiol Lung Cell Mol Physiol 307:L471-81

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