Component VII - Pilot Studies The six projects proposed for the Pilot Study Component are thematically consistent with projects previously and currently supported by our Center. For example, the proposed study of the effects of zonisamide, a compound similar to topiramate, for controlling problem drinking is consistent with our Center's long-standing support of pharmacotherapy studies. In addition, the study of increasing physical exercise to help sedentary college students reduce problem drinking is consistent with our ongoing studies of individuals "at risk" for alcoholism. The basic science studies proposed by Drs. Conti and Shoemaker to examine the role of stress at different stages of development on later alcohol use are consistent with the Center's interest in basic science questions that relate to the etiology of alcoholism. The Pilot Study Program is managed by the PI and Executive Committee, with advice from the Scientific Advisory Group. Pilot studies are approved for funding on the basis of a competitive review procedure which closely approximates the NIH procedure. It begins with an open call for proposals that is circulated within the ARC, the department and to research groups in other areas of the Schools of Medicine and Dental Medicine. The ARC Executive Committee reviews each proposal to verify, at first, that it is consistent with the research objectives of the ARC. If the proposal is considered to be meritorious by the Executive Committee, it is forwarded to external reviewers. The likelihood that the proposed pilot study will support the development of a larger R01 proposal, a career development award or a future major component of future Center applications, is considered in combination with the proposal's scientific merit in the final funding decision. The progress to date of ARC-supported pilot studies is outstanding. Support from the pilot studies program during the current 5-year cycle has thus far yielded 11 publications, 12 scientific meeting presentations, and?most significantly?5 grant application submissions. We expect that the group of 6 studies proposed for the next cycle of the ARC will be similarly fruitful.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Comprehensive Center (P60)
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Special Emphasis Panel (ZAA1-BB)
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University of Connecticut
United States
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Alessi, Sheila M; Rash, Carla J; Petry, Nancy M (2016) A Randomized Trial of Adjunct mHealth Abstinence Reinforcement With Transdermal Nicotine and Counseling for Smoking Cessation. Nicotine Tob Res :
Petry, Nancy M; Rash, Carla J; Alessi, Sheila M (2016) A randomized controlled trial of brief interventions for problem gambling in substance abuse treatment patients. J Consult Clin Psychol 84:874-86
Rash, Carla J; Burki, Madison; Montezuma-Rusca, Jairo M et al. (2016) A retrospective and prospective analysis of trading sex for drugs or money in women substance abuse treatment patients. Drug Alcohol Depend 162:182-9
Walter, Kimberly N; Petry, Nancy M (2016) Motivation and Contingency Management Treatments for Substance Use Disorders. Curr Top Behav Neurosci 27:569-81
Milivojevic, Verica; Fox, Helen C; Sofuoglu, Mehmet et al. (2016) Effects of progesterone stimulated allopregnanolone on craving and stress response in cocaine dependent men and women. Psychoneuroendocrinology 65:44-53
Rash, Carla J; Weinstock, Jeremiah; Van Patten, Ryan (2016) A review of gambling disorder and substance use disorders. Subst Abuse Rehabil 7:3-13
Stinchfield, Randy; McCready, John; Turner, Nigel E et al. (2016) Reliability, Validity, and Classification Accuracy of the DSM-5 Diagnostic Criteria for Gambling Disorder and Comparison to DSM-IV. J Gambl Stud 32:905-22
Weiss, Nicole H; Bold, Krysten W; Sullivan, Tami P et al. (2016) Testing Bidirectional Associations among Emotion Regulation Strategies and Substance Use: A Daily Diary Study. Addiction :
Becker, Sara J; Squires, Daniel D; Strong, David R et al. (2016) Training opioid addiction treatment providers to adopt contingency management: A prospective pilot trial of a comprehensive implementation science approach. Subst Abus 37:134-40
Carroll, Kathleen M; Nich, Charla; Petry, Nancy M et al. (2016) A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence. Drug Alcohol Depend 160:135-42

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