The Information Dissemination Core C004 proposes three interrelated specific aims designed to advance NIAAA's mission of translating and disseminating research findings to health care providers, researchers, policymakers and the public. All of the Core's activities are targeted especially to under-represented and/or disadvantaged groups.
Specific Aim 1 : K-12 Education & Outreach. The principal goal is to provide K-12th grade students and their teachers with information about alcohol, the brain, and neuroscience. We propose age-appropriate activities that present information about how the brain works and how alcohol can affect it. The activities promote keeping one's brain safe, making informed choices, meeting male and female neuroscientist role models, and pursuing careers in neuroscience and alcohol research in particular.
Aim 1 focuses especially on adolescent vulnerability to alcohol abuse by utilizing material from the NIAAA curriculum, Understanding Alcohol: Investigations into Biology and Behavior, and from other sources. New for the renewal we propose to prepare high school students to make presentations in their school's respective feeder middle schools. The high school near-peers integrate the changing adolescent brain, neuroscience of alcohol and drugs, decision- making, and how to transition successfully to high school. We will partner with the On Track OHSU! program which begins long-term mentoring in middle schools in order to bring more diverse and disadvantaged students into health science research and clinical practice. We propose to continue a novel neuroscience and safety curriculum developed by this PARC Core for Kindergarten-3rd graders, with more advanced activities to be added for 4th and 5th graders. At the high school level we continue a Genetics and Alcohol seminar that is adaptable from lab visits to in-school classroom visits to auditorium talks. Two new proposed high school activities include: a PARC-created drunk driving simulator used to teach experimental methods, and an interactive sports team seminar focusing on the effects of alcohol on athletic training, performance, and recovery.
Specific Aim 2 : Training in Alcohol Research. Here, we propose to provide training and laboratory experience in alcohol research to high school, undergraduate, graduate, and post-doctoral students. Training the next generations of alcohol researchers has been a major commitment of many PARC investigators, some for over 30 years.
Specific Aim 3 : Dissemination and Translational Interface. In this Aim we propose to coordinate and share the findings of the Center, and alcohol research results in general, through a variety of well-established mechanisms with scientific colleagues, policymakers, and diverse communities.
Aim 3 proposes activities and resources including: professional and lay publications; the Center website for professionals and the general public; the PARC Library; inclusion of PARC investigators in the University's speakers and scientific experts bureau; dissemination of PARC findings to the media; professional conferences; and outcome review of the education and outreach activities of the Core.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Comprehensive Center (P60)
Project #
2P60AA010760-21
Application #
8977315
Study Section
Special Emphasis Panel (ZAA1-GG (50))
Project Start
Project End
Budget Start
2016-01-01
Budget End
2016-12-31
Support Year
21
Fiscal Year
2016
Total Cost
$112,474
Indirect Cost
$23,209
Name
Oregon Health and Science University
Department
Type
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Colville, Alexandre M; Iancu, Ovidiu D; Lockwood, Denesa R et al. (2018) Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders. Front Genet 9:300
Xu, Ting; Falchier, Arnaud; Sullivan, Elinor L et al. (2018) Delineating the Macroscale Areal Organization of the Macaque Cortex In Vivo. Cell Rep 23:429-441
Iancu, Ovidiu D; Colville, Alexander; Walter, Nicole A R et al. (2018) On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome. Addict Biol 23:196-205
Morales, Angelica M; Jones, Scott A; Ehlers, Alissa et al. (2018) Ventral striatal response during decision making involving risk and reward is associated with future binge drinking in adolescents. Neuropsychopharmacology 43:1884-1890
Gavin, David P; Hashimoto, Joel G; Lazar, Nathan H et al. (2018) Stable Histone Methylation Changes at Proteoglycan Network Genes Following Ethanol Exposure. Front Genet 9:346
Purohit, Kush; Parekh, Puja K; Kern, Joseph et al. (2018) Pharmacogenetic Manipulation of the Nucleus Accumbens Alters Binge-Like Alcohol Drinking in Mice. Alcohol Clin Exp Res 42:879-888
Müller-Oehring, Eva M; Kwon, Dongjin; Nagel, Bonnie J et al. (2018) Influences of Age, Sex, and Moderate Alcohol Drinking on the Intrinsic Functional Architecture of Adolescent Brains. Cereb Cortex 28:1049-1063
Iancu, Ovidiu Dan; Colville, Alex M; Wilmot, Beth et al. (2018) Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs. Alcohol Clin Exp Res :
Kafkafi, Neri; Agassi, Joseph; Chesler, Elissa J et al. (2018) Reproducibility and replicability of rodent phenotyping in preclinical studies. Neurosci Biobehav Rev 87:218-232
Qiu, J; Wagner, E J; Rønnekleiv, O K et al. (2018) Insulin and leptin excite anorexigenic pro-opiomelanocortin neurones via activation of TRPC5 channels. J Neuroendocrinol 30:

Showing the most recent 10 out of 291 publications